Chemical Constituents and an Alternative Medicinal Veterinary Herbal Soap Made from Senna macranthera

Upon undergoing biomonitoring, the most active dichloromethane extract retrieved from Senna macranthera roots led to the isolation of three main compounds: emodine, physione, and chrysophanol. In this sequence, these compounds revealed a potential antibacterial activity against Staphylococcus aureus...

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Bibliographic Details
Published in:Evidence-based complementary and alternative medicine 2015-01, Vol.2015 (2015), p.1-6
Main Authors: Diaz, Marisa Alves Nogueira, Lima, Samia, Pais Siqueira, Raoni, Faria Maia, Thalita de, Purgato, Gislaine Aparecida, Inoue Andrade, Flávia, Diaz, Gaspar
Format: Article
Language:English
Subjects:
Agriculture
Animals
Antibacterial agents
Antimicrobial agents
Bioassays
Biofilms
Biological monitoring
Contamination
Health aspects
Herbal medicine
Infection
Laboratories
Metabolites
NMR
Nuclear magnetic resonance
Soap
Staphylococcus aureus
Staphylococcus aureus infections
Staphylococcus infections
Veterinary medicine
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Summary:Upon undergoing biomonitoring, the most active dichloromethane extract retrieved from Senna macranthera roots led to the isolation of three main compounds: emodine, physione, and chrysophanol. In this sequence, these compounds revealed a potential antibacterial activity against Staphylococcus aureus strains isolated from animals with mastitis infections with minimum inhibitory concentration (MIC) values of 20, 90, and 90 μg mL−1, respectively. Therefore, an herbal soap was also produced from this same active extract. This soap was tested in vitro using gloves contaminated by animals with bovine mastitis that had been discarded after use by milkers and showed similar results to previously tested compounds. These results indicate the potential of this plant as an alternative veterinary medicine for the production of antibacterial soaps that aimed at controlling bovine mastitis infections in small Brazilian farms.
ISSN:1741-427X
1741-4288
DOI:10.1155/2015/217598