Optimization of the convection volume in online post-dilution haemodiafiltration: practical and technical issues

In post-dilution online haemodiafiltration (ol-HDF), a relationship has been demonstrated between the magnitude of the convection volume and survival. However, to achieve high convection volumes (>22 L per session) detailed notion of its determining factors is highly desirable. This manuscript su...

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Published in:Clinical kidney journal 2015-04, Vol.8 (2), p.191-198
Main Authors: Chapdelaine, Isabelle, de Roij van Zuijdewijn, Camiel L.M., Mostovaya, Ira M., Lévesque, Renée, Davenport, Andrew, Blankestijn, Peter J., Wanner, Christoph, Nubé, Menso J., Grooteman, Muriel P.C.
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Language:English
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Summary:In post-dilution online haemodiafiltration (ol-HDF), a relationship has been demonstrated between the magnitude of the convection volume and survival. However, to achieve high convection volumes (>22 L per session) detailed notion of its determining factors is highly desirable. This manuscript summarizes practical problems and pitfalls that were encountered during the quest for high convection volumes. Specifically, it addresses issues such as type of vascular access, needles, blood flow rate, recirculation, filtration fraction, anticoagulation and dialysers. Finally, five of the main HDF systems in Europe are briefly described as far as HDF prescription and optimization of the convection volume is concerned.
ISSN:2048-8505
2048-8513
DOI:10.1093/ckj/sfv003