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Treatment of adynamic bone disease in a haemodialysis patient with teriparatide
Prevalence of adynamic bone disease (ABD), characterized by low bone turnover and absence or a reduced number of osteoblasts and osteoclasts, is increasing steadily over the last years. We present a dialysis patient, with recurrent bone fractures and biopsy-proven ABD, who was treated with teriparat...
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| Published in: | Clinical kidney journal 2015-04, Vol.8 (2), p.188-190 |
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| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c408t-6603fa0198115a4cf8eb920ac440a80ea275fb20516abb8d9c831430851ee81a3 |
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| cites | cdi_FETCH-LOGICAL-c408t-6603fa0198115a4cf8eb920ac440a80ea275fb20516abb8d9c831430851ee81a3 |
| container_end_page | 190 |
| container_issue | 2 |
| container_start_page | 188 |
| container_title | Clinical kidney journal |
| container_volume | 8 |
| creator | Giamalis, Panagiotis Economidou, Dominiki Dimitriadis, Chrysostomos Memmos, Dimitrios Papagianni, Aikaterini Efstratiadis, Georgios |
| description | Prevalence of adynamic bone disease (ABD), characterized by low bone turnover and absence or a reduced number of osteoblasts and osteoclasts, is increasing steadily over the last years. We present a dialysis patient, with recurrent bone fractures and biopsy-proven ABD, who was treated with teriparatide. Nine months after initiation of treatment, iPTH plasma levels increased to 520 pg/mL and a second bone biopsy revealed high bone turnover, normal mineralization and normal bone volume. Two years later, iPTH was 250–350 pg/dL and bone metabolism parameters within normal range. The probable utility of teriparatide in the treatment of ABD in dialysis patients is discussed. |
| doi_str_mv | 10.1093/ckj/sfv005 |
| format | article |
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| subjects | Contents |
| title | Treatment of adynamic bone disease in a haemodialysis patient with teriparatide |
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