Breast cancer associated with neurofibromatosis type 1: a case series and review of the literature

Neurofibromatosis type 1, also known as Von Recklinghausen's disease, is a rare neuroectodermal disease that mainly affects the skin and the nervous system. Patients with neurofibromatosis type 1 have a higher risk of developing various types of cancers, especially tumors derived from the embry...

Full description

Saved in:
Bibliographic Details
Published in:Journal of medical case reports 2015-03, Vol.9 (1), p.61-61, Article 61
Main Authors: Khalil, Jihane, Afif, Mohamed, Elkacemi, Hanan, Benoulaid, Meryem, Kebdani, Tayeb, Benjaafar, Noureddine
Format: Article
Language:English
Subjects:
Adult
Breast cancer
Breast Neoplasms - etiology
Breast Neoplasms - pathology
Carcinoma, Ductal, Breast - etiology
Carcinoma, Ductal, Breast - pathology
Care and treatment
Case Report
Case studies
Development and progression
Diagnosis
Female
Health aspects
Humans
Middle Aged
Neurofibromatosis
Neurofibromatosis 1 - complications
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Neurofibromatosis type 1, also known as Von Recklinghausen's disease, is a rare neuroectodermal disease that mainly affects the skin and the nervous system. Patients with neurofibromatosis type 1 have a higher risk of developing various types of cancers, especially tumors derived from the embryogenic neural crest. However, its association with breast cancer has seldom been reported. We report the cases of three white Arabic women diagnosed with neurofibromatosis type 1, with a median age of 40-years-old (range: 39 to 43), who sought treatment at our centre for breast cancer. The association between neurofibromatosis type 1 and breast cancer is uncommon. In our case series we readdress this association through a literature review.
ISSN:1752-1947
1752-1947
DOI:10.1186/s13256-015-0533-8