Influences of hyperlipidemia history on stroke outcome; a retrospective cohort study based on the Kyoto Stroke Registry

• Published in: BMC neurology 2015-03, Vol.15 (1), p.44-44, Article 44
• Main Authors: Shigematsu, Kazuo, Watanabe, Yoshiyuki, Nakano, Hiromi
• Format: Article
• Language: English
• Subjects: Aged; Aged, 80 and over; Care and treatment; Cerebral Hemorrhage - epidemiology; Cerebral Hemorrhage - mortality; Cerebral Infarction - epidemiology; Cerebral Infarction - mortality; Cohort Studies; Comorbidity; Comparative analysis; Complications and side effects; Female; Humans; Hyperlipidemia; Hyperlipidemias - epidemiology; Incidence; Logistic Models; Male; Middle Aged; Odds Ratio; Proportional Hazards Models; Recovery of Function; Registries; Retrospective Studies; Risk Factors; Stroke (Disease); Stroke - epidemiology; Stroke - mortality; Subarachnoid Hemorrhage - epidemiology; Subarachnoid Hemorrhage - mortality
• ISSN: 1471-2377; 1471-2377
• DOI: 10.1186/s12883-015-0297-1

Although hyperlipidemia is known as a risk factor of stroke, its effects on the outcome are unknown. The aim of the study is to clarify the influences of hyperlipidemia on the stroke early outcome by estimating odds ratio (OR) for sequelae requiring care and hazard ratio (HR) for death. A total of 12617 stroke patients registered in the Kyoto Stroke Registry with information on a hyperlipidemia history. We compared patients who had hyperlipidemia history and patients who hadn't. The OR for remaining sequelae requiring certain care on 30 day after stroke was calculated using a logistic regression in stroke as a whole and in each stroke subtype; cerebral infarction (CI), cerebral hemorrhage (CH) and subarachnoid hemorrhage (SAH). The HR for death within 30 day after stroke was estimated by the Cox regression. The OR (95% confidence interval) for remaining sequelae 30 days after stroke was 0.66 (0.60-0.73, p