Strategies for Improving Animal Models for Regenerative Medicine

The field of regenerative medicine is moving toward translation to clinical practice. However, there are still knowledge gaps and safety concerns regarding stem cell-based therapies. Improving large animal models and methods for transplantation, engraftment, and imaging should help address these iss...

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Bibliographic Details
Published in:Cell stem cell 2013-03, Vol.12 (3), p.271-274
Main Authors: Cibelli, Jose, Emborg, Marina E., Prockop, Darwin J., Roberts, Michael, Schatten, Gerald, Rao, Mahendra, Harding, John, Mirochnitchenko, Oleg
Format: Article
Language:English
Subjects:
Animals
Models, Animal
Regenerative Medicine - methods
Stem Cell Transplantation
Stem Cells - cytology
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Summary:The field of regenerative medicine is moving toward translation to clinical practice. However, there are still knowledge gaps and safety concerns regarding stem cell-based therapies. Improving large animal models and methods for transplantation, engraftment, and imaging should help address these issues, facilitating eventual use of stem cells in the clinic.
ISSN:1934-5909
1875-9777
DOI:10.1016/j.stem.2013.01.004