Constrained Peptides as Miniature Protein Structures

This paper discusses the recent developments of protein engineering using both covalent and noncovalent bonds to constrain peptides, forcing them into designed protein secondary structures. These constrained peptides subsequently can be used as peptidomimetics for biological functions such as regula...

Full description

Saved in:
Bibliographic Details
Published in:ISRN biochemistry 2012, Vol.2012 (2012), p.1-15
Main Author: Yin, Hang
Format: Article
Language:English
Subjects:
Review
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This paper discusses the recent developments of protein engineering using both covalent and noncovalent bonds to constrain peptides, forcing them into designed protein secondary structures. These constrained peptides subsequently can be used as peptidomimetics for biological functions such as regulations of protein-protein interactions.
ISSN:2090-7729
2090-7729
DOI:10.5402/2012/692190