Clinical features of infectious endophthalmitis in South Korea: a five-year multicenter study

• Published in: BMC infectious diseases 2015-04, Vol.15 (1), p.177-177, Article 177
• Main Authors: Nam, Ki Yup, Lee, Joo Eun, Lee, Ji Eun, Jeung, Woo Jin, Park, Jung Min, Park, Jong Moon, Chung, In Young, Han, Yong Seop, Yun, Il Han, Kim, Hyun Wong, Byon, Ik Soo, Oum, Boo Sup, Yoon, Hee Sung, Park, Dong, Yu, Byeng Chul, Park, Eun-Kee, Lee, Hu-Jang, Lee, Sang Joon
• Format: Article
• Language: English
• Subjects: Adult; Age Distribution; Aged; Anti-Bacterial Agents - therapeutic use; Care and treatment; Cataract; Cataract Extraction; Cohort Studies; Comorbidity; Corneal Injuries - epidemiology; Diabetes Mellitus - epidemiology; Diagnosis; Endophthalmitis; Endophthalmitis - epidemiology; Endophthalmitis - therapy; Eye Infections, Bacterial - epidemiology; Eye Infections, Bacterial - therapy; Female; Humans; Hypertension; Hypertension - epidemiology; Intravitreal Injections; Liver; Liver Abscess - epidemiology; Male; Middle Aged; Republic of Korea - epidemiology; Retrospective Studies; Seasons; Sex Distribution; Surgery; Surgical Wound Infection - epidemiology; Visual Acuity; Vitrectomy - methods
• ISSN: 1471-2334; 1471-2334
• DOI: 10.1186/s12879-015-0900-5

To investigate clinical features of infectious endophthalmitis over five years in a South Korean population. Medical records of consecutive patients diagnosed with infectious endophthalmitis at eight institutions located in Gyeongsangnam-do and Pusan city between January 1, 2004 and July 31, 2010 were reviewed. A total of 197 patients were diagnosed and treated. An average of 30.0 infectious endophthalmitis per year was developed. The annual incidence rate of postoperative endophthalmitis during 2006~2009 was 0.037%. The ratios of male to female and right to left were 50.2%: 49.8 % and 54.8%: 43.2%, respectively. Eighth decade and spring were the peak age (36.6%) and season (32.0%) to develop the infectious endophthalmitis. The most common past history in systemic disease was hypertension (40.4%), followed by diabetes (23.4%). Cataract operation (60.4%) was the most common cause, among which most of them was uneventful phacoemulsification (95.9%). Corneal laceration (51.6%) and liver abscess (42.9%) were the most common causes of traumatic and endogenous endophthalmitis, respectively. The percentages of patients with initial and final visual acuity less than counting fingers were 62.6% and 35.2%, respectively. Treatment with vitrectomy with or without intravitreal antibiotics injection was administered to 72.6% of patients, while 17.3% received intravitreal antibiotics only. Our study revealed that the development of infectious endophthalmitis was related with seasonal variation and increased during our study period. Pars plana vitrectomy was preferred for the treatment of infectious endophthalmitis in South Korea.