Molecular epidemiology of human rhinovirus infections in the pediatric emergency department

Highlights • We analyzed rhinovirus (HRV) illness in children at a hospital emergency department. • HRV-C was associated with lower respiratory tract illness (LRTI) compared to HRV-A. • Specific HRV-A and C genotypes were more strongly associated with LRTI. • Patients with multiple illness episodes...

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Bibliographic Details
Published in:Journal of clinical virology 2015-01, Vol.62, p.25-31
Main Authors: Martin, Emily K, Kuypers, Jane, Chu, Helen Y, Lacombe, Kirsten, Qin, Xuan, Strelitz, Bonnie, Bradford, Miranda, Jones, Charla, Klein, Eileen J, Englund, Janet A
Format: Article
Language:English
Subjects:
Allergy and Immunology
Child, Preschool
Emergency department
Emergency Service, Hospital
Enterovirus
Female
Genotype
Genotyping
HRV-C
Human rhinovirus
Humans
Infant
Infant, Newborn
Infectious Disease
Lower respiratory tract infection
Male
Odds Ratio
Phylogeny
Picornaviridae Infections - diagnosis
Picornaviridae Infections - epidemiology
Picornaviridae Infections - virology
Rhinovirus - classification
Rhinovirus - genetics
Rhinovirus - isolation & purification
RNA, Viral
Seasons
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Summary:Highlights • We analyzed rhinovirus (HRV) illness in children at a hospital emergency department. • HRV-C was associated with lower respiratory tract illness (LRTI) compared to HRV-A. • Specific HRV-A and C genotypes were more strongly associated with LRTI. • Patients with multiple illness episodes had new HRV infections in each episode.
ISSN:1386-6532
1873-5967
DOI:10.1016/j.jcv.2014.11.006