Multiple sclerosis in US minority populations: Clinical practice insights

The heterogeneity of multiple sclerosis (MS) characteristics among various ethnic minority populations is a topic of recent interest. However, these populations are consistently underrepresented in clinical trials, leading to limited data on the effectiveness of treatments in these groups of patient...

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Bibliographic Details
Published in:Neurology. Clinical practice 2015-04, Vol.5 (2), p.132-142
Main Authors: Khan, Omar, Williams, Mitzi J, Amezcua, Lilyana, Javed, Adil, Larsen, Kristin E, Smrtka, Jennifer M
Format: Article
Language:English
Subjects:
Clinical and Ethical Challenges
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Summary:The heterogeneity of multiple sclerosis (MS) characteristics among various ethnic minority populations is a topic of recent interest. However, these populations are consistently underrepresented in clinical trials, leading to limited data on the effectiveness of treatments in these groups of patients and lack of an evidence-based approach to treatment. In order to achieve optimal disease management in the ethnic minority MS populations, a better understanding of the regional, socioeconomic, and cultural influences that result in underrepresentation of these groups in clinical trials is needed. Furthermore, it would be beneficial to identify the genetic factors that influence disease disparity in these minority populations. Suggestions for the identification and implementation of best practices for fostering the trust of ethnic minority patients with MS and enhancing their participation in clinical trials are offered.
ISSN:2163-0402
2163-0933
DOI:10.1212/CPJ.0000000000000112