A rare case of a splenic hamartoma in a patient with a huge palpable abdominal mass: a case report

Splenic hamartoma is a primary benign tumor of the spleen, which is often found incidentally. Splenic hamartomas are very rare, with approximately 150 cases documented in the literature to date. They represent benign vascular proliferation. Histological findings consist of disorganized stroma and va...

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Bibliographic Details
Published in:Journal of medical case reports 2015-01, Vol.9 (1), p.4-4, Article 4
Main Authors: Vlachou, Paraskevi, Fagkrezos, Dimitris, Tzivelopoulou, Anastasia, Kyriakopoulou, Georgia, Maniatis, Petros, Triantopoulou, Charikleia, Papailiou, John
Format: Article
Language:English
Subjects:
Abdomen
Adult
Care and treatment
Case Report
Case studies
CT imaging
Diagnosis
Diagnosis, Differential
Female
Hamartoma
Hamartoma - diagnosis
Hamartoma - diagnostic imaging
Hamartoma - pathology
Hamartoma - surgery
Health aspects
Histochemistry
Humans
Incidental Findings
Palpation
Patient outcomes
Risk factors
Splenectomy
Splenic Diseases - diagnosis
Splenic Diseases - diagnostic imaging
Splenic Diseases - pathology
Splenic Diseases - surgery
Tomography, X-Ray Computed
Treatment Outcome
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Summary:Splenic hamartoma is a primary benign tumor of the spleen, which is often found incidentally. Splenic hamartomas are very rare, with approximately 150 cases documented in the literature to date. They represent benign vascular proliferation. Histological findings consist of disorganized stroma and vascular channels of varying width, with or without lymphoid follicles. We present the case of a 39-year-old Greek woman, with no significant medical history, who was diagnosed incidentally with an enormous splenic hamartoma on computed tomography, finally confirmed by surgery and histopathology. Hamartomas are benign lesions, and it is important to differentiate them from malignancy. Hamartoma represents a rare vascular entity characterized by a cluster of differentiation 8-positive immunophenotype. It is usually asymptomatic but large hamartomas may present with symptoms such as hemopoetic disorders, which resolve after splenectomy. It is important for radiologists to be able to differentiate splenic hamartoma from malignant entities.
ISSN:1752-1947
1752-1947
DOI:10.1186/1752-1947-9-4