Relationship between bone density and bone metabolism in adolescent idiopathic scoliosis

Several authors have confirmed that 27 to 38% of AIS patients had osteopenia. But few studies have assessed bone metabolism in AIS. This study assessed bone mineral density and bone metabolism in AIS patients using the bone metabolism markers, BAP and TRAP5b. The subjects were 49 consecutive adolesc...

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Bibliographic Details
Published in:Scoliosis 2015-03, Vol.10 (1), p.9-9, Article 9
Main Authors: Ishida, Ko, Aota, Yoichi, Mitsugi, Naoto, Kono, Motonori, Higashi, Takayuki, Kawai, Takuya, Yamada, Katsutaka, Niimura, Takanori, Kaneko, Kanichiro, Tanabe, Hironori, Ito, Yohei, Katsuhata, Tomoyuki, Saito, Tomoyuki
Format: Article
Language:English
Subjects:
Analysis
Bones
Care and treatment
Density
Medical research
Medicine, Experimental
Osteoporosis
Physiological aspects
Risk factors
Scoliosis
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Summary:Several authors have confirmed that 27 to 38% of AIS patients had osteopenia. But few studies have assessed bone metabolism in AIS. This study assessed bone mineral density and bone metabolism in AIS patients using the bone metabolism markers, BAP and TRAP5b. The subjects were 49 consecutive adolescent AIS patients seen at our institutes between March 2012 and September 2013. Sixty-five percent of AIS patients had osteopenia or osteoporosis and 59% of AIS patients had high values for TRAP5b. The AIS patients with high values of TRAP5b had lower Z scores than those with normal values of TRAP5b. Higher rates of bone resorption are associated with low bone density in AIS patients.
ISSN:1748-7161
1748-7161
DOI:10.1186/s13013-015-0033-z