The etiology and outcome of non-traumatic coma in critical care: a systematic review

Non-traumatic coma (NTC) is a serious condition requiring swift medical or surgical decision making upon arrival at the emergency department. Knowledge of the most frequent etiologies of NTC and associated mortality might improve the management of these patients. Here, we present the results of a sy...

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Bibliographic Details
Published in:BMC anesthesiology 2015-04, Vol.15 (1), p.65-65, Article 65
Main Authors: Horsting, Marlene Wb B, Franken, Mira D, Meulenbelt, Jan, van Klei, Wilton A, de Lange, Dylan W
Format: Article
Language:English
Subjects:
Care and treatment
Causes and theories of causation
Coma - etiology
Coma - mortality
Critical Care
Decision-making
Development and progression
Diseases
Epidemiologic Methods
Epilepsy - mortality
Health aspects
Humans
Hypoxia - mortality
Medical research
Medicine, Experimental
Persistent Vegetative State - mortality
Poisoning
Poisoning - mortality
Prevalence
Prognosis
Stroke - mortality
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Summary:Non-traumatic coma (NTC) is a serious condition requiring swift medical or surgical decision making upon arrival at the emergency department. Knowledge of the most frequent etiologies of NTC and associated mortality might improve the management of these patients. Here, we present the results of a systematic literature search on the etiologies and prognosis of NTC. Two reviewers independently performed a systematic literature search in the Pubmed, Embase and Cochrane databases with subsequent reference and citation checking. Inclusion criteria were retrospective or prospective observational studies on NTC, which reported on etiologies and prognostic information of patients admitted to the emergency department or intensive care unit. Eventually, 14 studies with enough data on NTC, were selected for this systematic literature review. The most common causes of NTC were stroke (6-54%), post-anoxic coma (3-42%), poisoning (
ISSN:1471-2253
1471-2253
DOI:10.1186/s12871-015-0041-9