Premature progesterone rise at human chorionic gonadotropin triggering day has no correlation with intracytoplasmic sperm injection outcome

Background: Premature luteinization during in vitro fertilization was commonly happened before the introduction of GnRh analogues. High level of unwanted progesterone is associated with adverse pregnancy outcome and is thought to be induced by inappropriate LH elevation. Objective: To evaluate the p...

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Bibliographic Details
Published in:International journal of reproductive biomedicine (Yazd, Iran) Iran), 2015-02, Vol.13 (2), p.79-84
Main Authors: Saharkhiz, Nasrin, Salehpour, Saghar, Tavasoli, Mahboobeh, Aghighi, Ali
Format: Article
Language:English
Subjects:
GnRh agonist
GnRh antagonist
HCG triggering
Intracytoplasmic sperm injection
Original
Progesterone rise
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Summary:Background: Premature luteinization during in vitro fertilization was commonly happened before the introduction of GnRh analogues. High level of unwanted progesterone is associated with adverse pregnancy outcome and is thought to be induced by inappropriate LH elevation. Objective: To evaluate the progesterone level on the day of Human Chorionic Gonadotropin (HCG) triggering in GnRh agonist and antagonist protocols, and its correlation with clinical pregnancy rate and miscarriage rate. Materials and Methods: One hundred and seven women underwent intracytoplasmic sperm injection with long agonist protocol (n=46) or antagonist protocol (n=61). Blood sample was obtained from each patient for progesterone level measurement in HCG administration day, then patients were divided into two groups according to their serum progesterone levels on the HCG triggering day: progesterone level
ISSN:1680-6433
2476-4108
2476-3772
2008-2177