Preoperative CRP levels is not predictive early renal dysfunction after coronary artery bypass surgery

• Published in: International journal of clinical and experimental medicine 2015-01, Vol.8 (3), p.4146-4151
• Main Authors: Sahin, Veysel, Akpinar, Mehmet Besir, Sevim, Erol, Uyar, Ihsan Sami, Abacilar, Ahmet Feyzi, Uc, Halil, Tetik, Funda, Damar, Ertan, Okur, Faik Fevzi, Alayunt, Emin Alp
• Format: Article
• Language: English
• Subjects: Original
• ISSN: 1940-5901; 1940-5901

The aim of this retrospective study is to determine the correlation between preoperative CRP levels and the early renal dysfunction after cardiac surgery. From January 2012 to December 2013, values for preoperative CRP were available for 546 unselected patients undergoing cardiac operations. CRP was used to divide this cohort in two groups: a normal CRP levels group (Group I) of 432 patients with CRP of less than 0.5 mg/dL, and a high CRP levels group (group II) of 114 patients with a CRP of 0.5 mg/dL or more. Median CRP preoperative values were significantly different in the group II (2.49±1.03 mg/dL) than in the group I (0.32±0.14 mg/dL; P < 0.0001). Median CRP postoperative values were significantly different in the group I (17.62±2.99) than in the group II (23.13±3.01; P < 0.0001). Preoperative levels of serum blood urea nitrogen (BUN), creatinine and CrCl were not significantly different between group I and group II. Postoperative levels of BUN, Cr and CrCl between the two groups were not significantly different. The early Cr and CrCl levels after surgery are not significantly different in group I and group II. The early renal function after CABG is not correlated with the preoperative CRP levels.