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Cannabinoid abuse and addiction: Clinical and preclinical findings

Cannabinoid abuse disorders represent a widespread public health issue, but there are no approved medications for their treatment. This review describes efforts to understand the mechanisms of cannabinoid abuse and its adverse effects, to identify molecular targets for pharmacotherapy, and to evalua...

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Bibliographic Details
Published in:Clinical pharmacology and therapeutics 2015-06, Vol.97 (6), p.616-627
Main Authors: Panlilio, LV, Goldberg, SR, Justinova, Z
Format: Article
Language:English
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Summary:Cannabinoid abuse disorders represent a widespread public health issue, but there are no approved medications for their treatment. This review describes efforts to understand the mechanisms of cannabinoid abuse and its adverse effects, to identify molecular targets for pharmacotherapy, and to evaluate potential treatments in human volunteers and animal models of cannabinoid reward, withdrawal, and relapse.
ISSN:0009-9236
1532-6535
DOI:10.1002/cpt.118