GABAergic inhibition shapes SAM responses in rat auditory thalamus

Highlights • Medial geniculate body shows emergent properties in its coding of modulated stimuli. • A delicate balance of tonic GABA and NMDA signaling regulates coding of modulated signals. • Coding of higher modulation frequencies is uniquely shaped by GABA.

Saved in:
Bibliographic Details
Published in:Neuroscience 2015-07, Vol.299, p.146-155
Main Authors: Cai, R, Caspary, D.M
Format: Article
Language:English
Subjects:
Acoustic Stimulation
Animals
auditory thalamus
GABA-A Receptor Antagonists - pharmacology
gamma-Aminobutyric Acid - metabolism
Geniculate Bodies - drug effects
Geniculate Bodies - physiology
inhibition–excitation balance
Male
Neural Inhibition
Neurology
Neurons - drug effects
Neurons - physiology
Pyridazines - pharmacology
Rats
Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors
SAM response
Sound
Synaptic Transmission - drug effects
Valine - analogs & derivatives
Valine - pharmacology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Highlights • Medial geniculate body shows emergent properties in its coding of modulated stimuli. • A delicate balance of tonic GABA and NMDA signaling regulates coding of modulated signals. • Coding of higher modulation frequencies is uniquely shaped by GABA.
ISSN:0306-4522
1873-7544
DOI:10.1016/j.neuroscience.2015.04.062