Maternal zinc deficiency during pregnancy elevates the risks of fetal growth restriction: a population-based birth cohort study

We investigated the association between maternal zinc level during pregnancy and the risks of low birth weight (LBW) and small for gestational age (SGA) infants in a large population-based birth cohort study. In this study, 3187 pregnant women were recruited. For serum zinc level, 2940 pregnant wome...

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Bibliographic Details
Published in:Scientific reports 2015-06, Vol.5 (1), p.11262-11262, Article 11262
Main Authors: Wang, Hua, Hu, Yong-Fang, Hao, Jia-Hu, Chen, Yuan-Hua, Su, Pu-Yu, Wang, Ying, Yu, Zhen, Fu, Lin, Xu, Yuan-Yuan, Zhang, Cheng, Tao, Fang-Biao, Xu, De-Xiang
Format: Article
Language:English
Subjects:
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Adult
C-reactive protein
C-Reactive Protein - metabolism
Case-Control Studies
Cohort analysis
Cohort Studies
Female
Fetal Development
Fetal Growth Retardation - physiopathology
Fetuses
Gestational Age
Health risk assessment
Humanities and Social Sciences
Humans
Infant, Newborn
Infant, Small for Gestational Age - physiology
Infants
Interleukin 8
Interleukin-8 - blood
Low birth weight
Maternal-Fetal Exchange
multidisciplinary
Neonates
Newborn babies
Nutrient deficiency
Placenta - metabolism
Population studies
Population-based studies
Pregnancy
Prenatal development
Risk factors
Science
Small for gestational age
Transcription Factor RelA - biosynthesis
Tumor Necrosis Factor-alpha - blood
Up-Regulation
Zinc
Zinc - blood
Zinc - deficiency
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Summary:We investigated the association between maternal zinc level during pregnancy and the risks of low birth weight (LBW) and small for gestational age (SGA) infants in a large population-based birth cohort study. In this study, 3187 pregnant women were recruited. For serum zinc level, 2940 pregnant women were sufficient (≥56 μg/dL) and 247 deficient (
ISSN:2045-2322
2045-2322
DOI:10.1038/srep11262