Oesophageal cancer: exploring controversies overview of experts' opinions of Austria, Germany, France, Netherlands and Switzerland

Oesophageal carcinoma is a rare disease with often dismal prognosis. Despite multiple trials addressing specific issues, currently, many questions in management remain unanswered. This work aimed to specifically address areas in the management of oesophageal cancer where high level evidence is not a...

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Published in:Radiation oncology (London, England) England), 2015-05, Vol.10 (1), p.116-116, Article 116
Main Authors: Putora, Paul Martin, Bedenne, Laurent, Budach, Wilfried, Eisterer, Wolfgang, Van Der Gaast, Ate, Jäger, Robert, Van Lanschot, J Jan B, Mariette, Christophe, Schnider, Annelies, Stahl, Michael, Ruhstaller, Thomas
Format: Article
Language:English
Subjects:
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Cancer
Care and treatment
Chemoradiotherapy
Chemotherapy
Consensus
Diagnostic Imaging
Disease Management
Dissent and Disputes
Esophageal cancer
Esophageal Neoplasms - diagnosis
Esophageal Neoplasms - therapy
Esophagectomy - methods
Europe
Humans
Multimodal Imaging
Neoadjuvant Therapy
Neoplasm Staging - methods
Pets
Prognosis
Radiotherapy
Radiotherapy - methods
Remission Induction
Societies, Medical
Surveys
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Summary:Oesophageal carcinoma is a rare disease with often dismal prognosis. Despite multiple trials addressing specific issues, currently, many questions in management remain unanswered. This work aimed to specifically address areas in the management of oesophageal cancer where high level evidence is not available, performing trials is very demanding and for many questions high-level evidence will not be available in the forseeable future. Two experts of each national, oesophageal cancer research group from Austria, France, Germany, the Netherlands and Switzerland were asked to provide statements to controversial issues. After an initial survey, further questions were formulated and answered by all experts. The answers were then discussed and qualitatively analysed for consensus and controversy. Topics such as indications for PET-CT, reasons for induction chemotherapy, radiotherapy dose, the choice of definitive chemo-radiotherapy versus surgery in squamous cell cancer, the role of radiotherapy in adenocarcinoma and selected surgical issues were identified as topics of interest and discussed. Areas of significant controversy exist in the management of oesophageal cancer, mostly due to high-level evidence. This is not expected to change in the upcoming years.
ISSN:1748-717X
1748-717X
DOI:10.1186/s13014-015-0418-4