Synthetic Androgens as Designer Supplements

Anabolic androgenic steroids (AAS) are some of the most common performance enhancing drugs (PED) among society. Despite the broad spectrum of adverse effects and legal consequences, AAS are illicitly marketed and distributed in many countries. To circumvent existing laws, the chemical structure of A...

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Bibliographic Details
Published in:Current neuropharmacology 2015-01, Vol.13 (1), p.89-100
Main Authors: Joseph, Jan Felix, Parr, Maria Kristina
Format: Article
Language:English
Subjects:
Anabolic Agents - chemistry
Anabolic Agents - pharmacology
Designer Drugs - adverse effects
Designer Drugs - chemistry
Designer Drugs - pharmacology
Dietary Supplements - adverse effects
Humans
Steroids - adverse effects
Steroids - chemistry
Steroids - pharmacology
Substance-Related Disorders - epidemiology
Testosterone Congeners - adverse effects
Testosterone Congeners - chemistry
Testosterone Congeners - pharmacology
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Summary:Anabolic androgenic steroids (AAS) are some of the most common performance enhancing drugs (PED) among society. Despite the broad spectrum of adverse effects and legal consequences, AAS are illicitly marketed and distributed in many countries. To circumvent existing laws, the chemical structure of AAS is modified and these designer steroids are sold as nutritional supplements mainly over the Internet. Several side effects are linked with AAS abuse. Only little is known about the pharmacological effects and metabolism of unapproved steroids due to the absence of clinical studies. The large number of designer steroid findings in dietary supplements and the detection of new compounds combined with legal loopholes for their distribution in many countries show that stricter regulations and better information policy are needed.
ISSN:1570-159X
1875-6190
DOI:10.2174/1570159X13666141210224756