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Synthetic Androgens as Designer Supplements
Anabolic androgenic steroids (AAS) are some of the most common performance enhancing drugs (PED) among society. Despite the broad spectrum of adverse effects and legal consequences, AAS are illicitly marketed and distributed in many countries. To circumvent existing laws, the chemical structure of A...
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Published in: | Current neuropharmacology 2015-01, Vol.13 (1), p.89-100 |
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creator | Joseph, Jan Felix Parr, Maria Kristina |
description | Anabolic androgenic steroids (AAS) are some of the most common performance
enhancing drugs (PED) among society. Despite the broad spectrum of adverse effects and legal
consequences, AAS are illicitly marketed and distributed in many countries. To circumvent existing
laws, the chemical structure of AAS is modified and these designer steroids are sold as nutritional
supplements mainly over the Internet. Several side effects are linked with AAS abuse. Only little is
known about the pharmacological effects and metabolism of unapproved steroids due to the absence
of clinical studies. The large number of designer steroid findings in dietary supplements and the
detection of new compounds combined with legal loopholes for their distribution in many countries
show that stricter regulations and better information policy are needed. |
doi_str_mv | 10.2174/1570159X13666141210224756 |
format | article |
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enhancing drugs (PED) among society. Despite the broad spectrum of adverse effects and legal
consequences, AAS are illicitly marketed and distributed in many countries. To circumvent existing
laws, the chemical structure of AAS is modified and these designer steroids are sold as nutritional
supplements mainly over the Internet. Several side effects are linked with AAS abuse. Only little is
known about the pharmacological effects and metabolism of unapproved steroids due to the absence
of clinical studies. The large number of designer steroid findings in dietary supplements and the
detection of new compounds combined with legal loopholes for their distribution in many countries
show that stricter regulations and better information policy are needed.</description><identifier>ISSN: 1570-159X</identifier><identifier>EISSN: 1875-6190</identifier><identifier>DOI: 10.2174/1570159X13666141210224756</identifier><identifier>PMID: 26074745</identifier><language>eng</language><publisher>United Arab Emirates: Bentham Science Publishers Ltd</publisher><subject>Anabolic Agents - chemistry ; Anabolic Agents - pharmacology ; Designer Drugs - adverse effects ; Designer Drugs - chemistry ; Designer Drugs - pharmacology ; Dietary Supplements - adverse effects ; Humans ; Steroids - adverse effects ; Steroids - chemistry ; Steroids - pharmacology ; Substance-Related Disorders - epidemiology ; Testosterone Congeners - adverse effects ; Testosterone Congeners - chemistry ; Testosterone Congeners - pharmacology</subject><ispartof>Current neuropharmacology, 2015-01, Vol.13 (1), p.89-100</ispartof><rights>2015 Bentham Science Publishers 2015 Maria Kristina Parr</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b547t-5534df7c572accf5c88a158d7acfc6095b1e4910ce19d75e498986e9ecc142ff3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462045/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462045/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26074745$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Joseph, Jan Felix</creatorcontrib><creatorcontrib>Parr, Maria Kristina</creatorcontrib><title>Synthetic Androgens as Designer Supplements</title><title>Current neuropharmacology</title><addtitle>CN</addtitle><description>Anabolic androgenic steroids (AAS) are some of the most common performance
enhancing drugs (PED) among society. Despite the broad spectrum of adverse effects and legal
consequences, AAS are illicitly marketed and distributed in many countries. To circumvent existing
laws, the chemical structure of AAS is modified and these designer steroids are sold as nutritional
supplements mainly over the Internet. Several side effects are linked with AAS abuse. Only little is
known about the pharmacological effects and metabolism of unapproved steroids due to the absence
of clinical studies. The large number of designer steroid findings in dietary supplements and the
detection of new compounds combined with legal loopholes for their distribution in many countries
show that stricter regulations and better information policy are needed.</description><subject>Anabolic Agents - chemistry</subject><subject>Anabolic Agents - pharmacology</subject><subject>Designer Drugs - adverse effects</subject><subject>Designer Drugs - chemistry</subject><subject>Designer Drugs - pharmacology</subject><subject>Dietary Supplements - adverse effects</subject><subject>Humans</subject><subject>Steroids - adverse effects</subject><subject>Steroids - chemistry</subject><subject>Steroids - pharmacology</subject><subject>Substance-Related Disorders - epidemiology</subject><subject>Testosterone Congeners - adverse effects</subject><subject>Testosterone Congeners - chemistry</subject><subject>Testosterone Congeners - pharmacology</subject><issn>1570-159X</issn><issn>1875-6190</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNp1kU1v1DAQhiMEoh_wF9ByQ0IBj-OvXJCq0gJSpR4KEreR15lsAokd7KSrnvnj9bJlBYee_ErzzMzrd4riNbB3HLR4D1IzkPV3qJRSIIAD41xoqZ4Ux2C0LBXU7GnWmSt34FFxktIPxrg0XD8vjrhiWmghj4u3N3d-7mju3erMNzFsyKeVTauPlPqNp7i6WaZpoJH8nF4Uz1o7JHr58J4W3y4vvp5_Lq-uP305P7sq11LouZSyEk2rndTcOtdKZ4wFaRptXesUq-UaSNTAHEHdaJm1qY2impwDwdu2Oi0-7OdOy3qkxuXd0Q44xX608Q6D7fH_iu873IRbFEJxJmQe8OZhQAy_Fkozjn1yNAzWU1gSgjJ1lVMDk9F6j7oYUorUHtYAw13Y-GjYuffVvz4PnX_TzcDvPbDORjs7JteTd3QAu3mecLvdIi2RftpEA7kZXRgxTOSXOGTt59yLUzdhPk0ktDHfaiDsU_J_vOHOHN6GYRkJodoVliwwTXZDmD96Dwwmrl8</recordid><startdate>20150101</startdate><enddate>20150101</enddate><creator>Joseph, Jan Felix</creator><creator>Parr, Maria Kristina</creator><general>Bentham Science Publishers Ltd</general><general>Bentham Science Publishers</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20150101</creationdate><title>Synthetic Androgens as Designer Supplements</title><author>Joseph, Jan Felix ; Parr, Maria Kristina</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b547t-5534df7c572accf5c88a158d7acfc6095b1e4910ce19d75e498986e9ecc142ff3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Anabolic Agents - chemistry</topic><topic>Anabolic Agents - pharmacology</topic><topic>Designer Drugs - adverse effects</topic><topic>Designer Drugs - chemistry</topic><topic>Designer Drugs - pharmacology</topic><topic>Dietary Supplements - adverse effects</topic><topic>Humans</topic><topic>Steroids - adverse effects</topic><topic>Steroids - chemistry</topic><topic>Steroids - pharmacology</topic><topic>Substance-Related Disorders - epidemiology</topic><topic>Testosterone Congeners - adverse effects</topic><topic>Testosterone Congeners - chemistry</topic><topic>Testosterone Congeners - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Joseph, Jan Felix</creatorcontrib><creatorcontrib>Parr, Maria Kristina</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Current neuropharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Joseph, Jan Felix</au><au>Parr, Maria Kristina</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Synthetic Androgens as Designer Supplements</atitle><jtitle>Current neuropharmacology</jtitle><addtitle>CN</addtitle><date>2015-01-01</date><risdate>2015</risdate><volume>13</volume><issue>1</issue><spage>89</spage><epage>100</epage><pages>89-100</pages><issn>1570-159X</issn><eissn>1875-6190</eissn><abstract>Anabolic androgenic steroids (AAS) are some of the most common performance
enhancing drugs (PED) among society. Despite the broad spectrum of adverse effects and legal
consequences, AAS are illicitly marketed and distributed in many countries. To circumvent existing
laws, the chemical structure of AAS is modified and these designer steroids are sold as nutritional
supplements mainly over the Internet. Several side effects are linked with AAS abuse. Only little is
known about the pharmacological effects and metabolism of unapproved steroids due to the absence
of clinical studies. The large number of designer steroid findings in dietary supplements and the
detection of new compounds combined with legal loopholes for their distribution in many countries
show that stricter regulations and better information policy are needed.</abstract><cop>United Arab Emirates</cop><pub>Bentham Science Publishers Ltd</pub><pmid>26074745</pmid><doi>10.2174/1570159X13666141210224756</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record> |
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source | PubMed Central |
subjects | Anabolic Agents - chemistry Anabolic Agents - pharmacology Designer Drugs - adverse effects Designer Drugs - chemistry Designer Drugs - pharmacology Dietary Supplements - adverse effects Humans Steroids - adverse effects Steroids - chemistry Steroids - pharmacology Substance-Related Disorders - epidemiology Testosterone Congeners - adverse effects Testosterone Congeners - chemistry Testosterone Congeners - pharmacology |
title | Synthetic Androgens as Designer Supplements |
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