Neurogenic Stress Cardiomyopathy After Aneurysmal Subarachnoid Hemorrhage

Background Neurogenic stress cardiomyopathy (NSC) is a known complication of aneurysmal subarachnoid hemorrhage (SAH). Detailed analyses of risk factors for its occurrence across large cohorts are relatively sparse. Methods A consecutive group of 300 patients with aneurysmal SAH was reviewed for the...

Full description

Saved in:
Bibliographic Details
Published in:World neurosurgery 2015-06, Vol.83 (6), p.880-885
Main Authors: Malik, Athar N, Gross, Bradley A, Rosalind Lai, Pui Man, Moses, Ziev B, Du, Rose
Format: Article
Language:English
Subjects:
Adult
Aged
Aneurysm
Cardiomyopathies - diagnostic imaging
Cardiomyopathies - etiology
Cohort Studies
Electrocardiography
Female
Humans
Male
Middle Aged
Myocardial
Neurogenic stress cardiomyopathy
Neurosurgery
Risk Factors
Stress
Stress, Physiological
Stroke Volume
Stunning
Subarachnoid hemorrhage
Subarachnoid Hemorrhage - complications
Treatment Outcome
Troponin
Troponin I - blood
Ultrasonography
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Neurogenic stress cardiomyopathy (NSC) is a known complication of aneurysmal subarachnoid hemorrhage (SAH). Detailed analyses of risk factors for its occurrence across large cohorts are relatively sparse. Methods A consecutive group of 300 patients with aneurysmal SAH was reviewed for the presence of markers of myocardial injury, including electrocardiogram changes (long QT, T-wave inversion), elevated plasma troponin levels (≥0.1), and echocardiogram findings (decreased ejection fraction and wall motion abnormalities). NSC was defined as the presence of at least 1 marker of myocardial injury. Univariate and multivariate analyses were conducted to assess the correlation of NSC and individual markers of myocardial injury with age, gender, medical comorbidities, medications, current smoking status, Hunt-Hess grade, and Fisher grade. Medical comorbidities were assessed based on reported medical history or reported use of comorbidity-specific medications at the time of presentation. Results Across the cohort, 27% of patients had a plasma troponin elevation of at least 0.1; 13%, a prolonged QT interval; 16%, new T-wave inversions; 18%, a depressed ejection fraction (
ISSN:1878-8750
1878-8769
DOI:10.1016/j.wneu.2015.01.013