Cardiovascular remodeling during long-term nocturnal home hemodialysis

Background Cardiovascular disease is the leading cause of morbidity and mortality in patients with kidney failure. Nocturnal home hemodialysis (NHD) is a form of kidney replacement therapy whereby hemodialysis is performed for at least 6-h overnight, at least 4 days per week. Little is known about t...

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Bibliographic Details
Published in:Clinical and experimental nephrology 2015-06, Vol.19 (3), p.514-520
Main Authors: Friesen, Tyler, Jassal, Davinder S., Zhu, Mike, Eng, Frederick, Rigatto, Claudio, Tangri, Navdeep, Sood, Manish M., Karlstedt, Erin, Premecz, Sheena, Komenda, Paul
Format: Article
Language:English
Subjects:
Adult
Atrial Remodeling
Echocardiography
Female
Hemodialysis, Home
Humans
Hypertrophy, Left Ventricular - diagnostic imaging
Hypertrophy, Left Ventricular - physiopathology
Kidney Failure, Chronic - complications
Kidney Failure, Chronic - therapy
Magnetic Resonance Imaging
Male
Medicine
Medicine & Public Health
Middle Aged
Nephrology
Original
Original Article
Self Care
Stroke Volume
Time Factors
Urology
Ventricular Dysfunction, Left - physiopathology
Ventricular Remodeling
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Summary:Background Cardiovascular disease is the leading cause of morbidity and mortality in patients with kidney failure. Nocturnal home hemodialysis (NHD) is a form of kidney replacement therapy whereby hemodialysis is performed for at least 6-h overnight, at least 4 days per week. Little is known about the effects of NHD on cardiovascular remodeling as assessed by transthoracic echocardiography (TTE) and cardiac magnetic resonance imaging (CMR). Objectives The primary objective of the study was to determine the long-term effects of NHD on cardiovascular remodeling using different imaging modalities over a one-year follow-up. Methods and results A total of 11 patients were included in the study (6 males, mean age 48 ± 16 years) between 2009 and 2011 inclusive at a single tertiary care center. All patients underwent TTE and CMR at baseline and after 1 year of NHD. Left ventricular mass index decreased significantly at 1 year by both TTE (152 ± 7–129 ± 8 g/m 2 , p  
ISSN:1342-1751
1437-7799
DOI:10.1007/s10157-014-0992-z