Thiamine as a metabolic resuscitator in septic shock: a randomized, double-blind, placebo-controlled, pilot trial

The objective was to determine whether the administration of thiamine mitigates elevated lactate levels in patients with septic shock. Thiamine is essential for aerobic metabolism and we have found that thiamine levels are low and inversely correlated with lactate levels in patients with sepsis.

Saved in:
Bibliographic Details
Published in:Critical care (London, England) England), 2015-01, Vol.19 (S1), p.P392-P392, Article P392
Main Authors: Donnino, M, Andersen, LW, Chase, M, Berg, KM, Giberson, TA, Smithline, H, Tidswell, M, Wolfe, R, Cocchi, M
Format: Article
Language:English
Subjects:
Double-blind studies
Evidence-based medicine
Mortality
Poster Presentation
Sepsis
Vitamin B
Vitamin deficiency
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The objective was to determine whether the administration of thiamine mitigates elevated lactate levels in patients with septic shock. Thiamine is essential for aerobic metabolism and we have found that thiamine levels are low and inversely correlated with lactate levels in patients with sepsis.
ISSN:1364-8535
1364-8535
1366-609X
1466-609X
DOI:10.1186/cc14472