Increased Regulatory T-Cell Percentage Contributes to Poor CD4+ Lymphocytes Recovery: A 2-Year Prospective Study After Introduction of Antiretroviral Therapy

Background.  The primary aim of this study was to determine the impact of regulatory T cells (Tregs) percentage on immune recovery in human immunodeficiency virus (HIV)-infected patients after antiretroviral therapy introduction. Methods.  A 2-year prospective study was conducted in HIV-1 chronicall...

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Bibliographic Details
Published in:Open forum infectious diseases 2015-04, Vol.2 (2), p.ofv063-ofv063
Main Authors: Saison, Julien, Maucort Boulch, Delphine, Chidiac, Christian, Demaret, Julie, Malcus, Christophe, Cotte, Laurent, Poitevin-Later, Francoise, Miailhes, Patrick, Venet, Fabienne, Trabaud, Mary Anne, Monneret, Guillaume, Ferry, Tristan
Format: Article
Language:English
Subjects:
Bacteriology
Immunology
Life Sciences
Major
Microbiology and Parasitology
Virology
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Summary:Background.  The primary aim of this study was to determine the impact of regulatory T cells (Tregs) percentage on immune recovery in human immunodeficiency virus (HIV)-infected patients after antiretroviral therapy introduction. Methods.  A 2-year prospective study was conducted in HIV-1 chronically infected naive patients with CD4 count
ISSN:2328-8957
2328-8957
DOI:10.1093/ofid/ofv063