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Durability and complications of photoselective vaporisation of the prostate with the 120W high performance system GreenLight™ lithium triborate laser
The aim of this study was to examine the durability of photoselective vaporisation of the prostate (PVP) with the 120W GreenLight HPS(®) laser (American Medical Systems, Minnetonka, MN, US), and to examine the incidence, nature and factors associated with complications from the procedure. Clinical r...
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Published in: | Annals of the Royal College of Surgeons of England 2014-07, Vol.96 (5), p.359-363 |
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creator | Batura, D Sahibzada, I Elkabir, J Feyisetan, O Izegbu, V Hellawell, G Webster, J |
description | The aim of this study was to examine the durability of photoselective vaporisation of the prostate (PVP) with the 120W GreenLight HPS(®) laser (American Medical Systems, Minnetonka, MN, US), and to examine the incidence, nature and factors associated with complications from the procedure.
Clinical records of PVP patients were reviewed to compare details between patients who developed complications and those who did not. Kaplan-Meier survival curves were used to assess durability. Cox regression was used to examine associations between complications and perioperative factors.
Successful outcomes were maintained in 84% of 117 patients at the 2-year follow-up appointment. Complication rates were low and comparable with transurethral resection of the prostate (TURP). Complications were developed by 18 patients (15.4%) over a mean follow-up duration of 20.8 months. The most common complications were residual prostate requiring another surgery (5/117, 4.3%) and urethral stricture (4/117, 3.4%). Patients with complications had significantly longer catheterisation duration. Length of hospital stay, lasing energy, pre and postoperative levels of prostate specific antigen (PSA), pre and postoperative maximum flow rate (Qmax), and age at surgery were not found to influence development of complications.
Results from PVP with an HPS(®) laser are durable. Complications are low and compare favourably with TURP. Lasing energy, PSA, Qmax, patient age and length of stay are not associated with development of complications. However, a longer postoperative catheterisation after PVP is associated with development of complications. |
doi_str_mv | 10.1308/003588414X13946184901047 |
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Clinical records of PVP patients were reviewed to compare details between patients who developed complications and those who did not. Kaplan-Meier survival curves were used to assess durability. Cox regression was used to examine associations between complications and perioperative factors.
Successful outcomes were maintained in 84% of 117 patients at the 2-year follow-up appointment. Complication rates were low and comparable with transurethral resection of the prostate (TURP). Complications were developed by 18 patients (15.4%) over a mean follow-up duration of 20.8 months. The most common complications were residual prostate requiring another surgery (5/117, 4.3%) and urethral stricture (4/117, 3.4%). Patients with complications had significantly longer catheterisation duration. Length of hospital stay, lasing energy, pre and postoperative levels of prostate specific antigen (PSA), pre and postoperative maximum flow rate (Qmax), and age at surgery were not found to influence development of complications.
Results from PVP with an HPS(®) laser are durable. Complications are low and compare favourably with TURP. Lasing energy, PSA, Qmax, patient age and length of stay are not associated with development of complications. However, a longer postoperative catheterisation after PVP is associated with development of complications.</description><identifier>ISSN: 0035-8843</identifier><identifier>EISSN: 1478-7083</identifier><identifier>DOI: 10.1308/003588414X13946184901047</identifier><identifier>PMID: 24992419</identifier><language>eng</language><publisher>England: BMJ Publishing Group LTD</publisher><subject>Adult ; Age Distribution ; Aged ; Antigens ; Bladder ; Borates ; High performance systems ; Humans ; Laser Therapy - adverse effects ; Laser Therapy - methods ; Lasers ; Length of Stay ; Lithium ; Lithium Compounds ; Male ; Middle Aged ; Operative Time ; Potassium ; Prospective Studies ; Prostate ; Prostatic Hyperplasia - surgery ; Retrospective Studies ; Sepsis ; Surgery ; Surgical outcomes ; Survival analysis ; Transurethral Resection of Prostate - adverse effects ; Transurethral Resection of Prostate - methods ; Urology ; Variables</subject><ispartof>Annals of the Royal College of Surgeons of England, 2014-07, Vol.96 (5), p.359-363</ispartof><rights>Copyright Royal College of Surgeons of England Jul 2014</rights><rights>Copyright © 2014, All rights reserved by the Royal College of Surgeons of England 2014</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c448t-aaa0cafe80c82353db9b2fcb090cae9f49ac83b4819c81ce46ee0ccf74743a003</citedby><cites>FETCH-LOGICAL-c448t-aaa0cafe80c82353db9b2fcb090cae9f49ac83b4819c81ce46ee0ccf74743a003</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473932/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473932/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24992419$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Batura, D</creatorcontrib><creatorcontrib>Sahibzada, I</creatorcontrib><creatorcontrib>Elkabir, J</creatorcontrib><creatorcontrib>Feyisetan, O</creatorcontrib><creatorcontrib>Izegbu, V</creatorcontrib><creatorcontrib>Hellawell, G</creatorcontrib><creatorcontrib>Webster, J</creatorcontrib><title>Durability and complications of photoselective vaporisation of the prostate with the 120W high performance system GreenLight™ lithium triborate laser</title><title>Annals of the Royal College of Surgeons of England</title><addtitle>Ann R Coll Surg Engl</addtitle><description>The aim of this study was to examine the durability of photoselective vaporisation of the prostate (PVP) with the 120W GreenLight HPS(®) laser (American Medical Systems, Minnetonka, MN, US), and to examine the incidence, nature and factors associated with complications from the procedure.
Clinical records of PVP patients were reviewed to compare details between patients who developed complications and those who did not. Kaplan-Meier survival curves were used to assess durability. Cox regression was used to examine associations between complications and perioperative factors.
Successful outcomes were maintained in 84% of 117 patients at the 2-year follow-up appointment. Complication rates were low and comparable with transurethral resection of the prostate (TURP). Complications were developed by 18 patients (15.4%) over a mean follow-up duration of 20.8 months. The most common complications were residual prostate requiring another surgery (5/117, 4.3%) and urethral stricture (4/117, 3.4%). Patients with complications had significantly longer catheterisation duration. Length of hospital stay, lasing energy, pre and postoperative levels of prostate specific antigen (PSA), pre and postoperative maximum flow rate (Qmax), and age at surgery were not found to influence development of complications.
Results from PVP with an HPS(®) laser are durable. Complications are low and compare favourably with TURP. Lasing energy, PSA, Qmax, patient age and length of stay are not associated with development of complications. However, a longer postoperative catheterisation after PVP is associated with development of complications.</description><subject>Adult</subject><subject>Age Distribution</subject><subject>Aged</subject><subject>Antigens</subject><subject>Bladder</subject><subject>Borates</subject><subject>High performance systems</subject><subject>Humans</subject><subject>Laser Therapy - adverse effects</subject><subject>Laser Therapy - methods</subject><subject>Lasers</subject><subject>Length of Stay</subject><subject>Lithium</subject><subject>Lithium Compounds</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Operative Time</subject><subject>Potassium</subject><subject>Prospective Studies</subject><subject>Prostate</subject><subject>Prostatic Hyperplasia - surgery</subject><subject>Retrospective Studies</subject><subject>Sepsis</subject><subject>Surgery</subject><subject>Surgical outcomes</subject><subject>Survival analysis</subject><subject>Transurethral Resection of Prostate - adverse effects</subject><subject>Transurethral Resection of Prostate - methods</subject><subject>Urology</subject><subject>Variables</subject><issn>0035-8843</issn><issn>1478-7083</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNp1kc-KFDEQxoMo7rj6ChLw4qU1_2ZSuQiy6ioMeFH0FtKZ6u0s3Z02SY_M3Xfw7qP5JGZ210UFT4H6fvWlqj5CKGfPuGTwnDG5BlBcfebSqA0HZRhnSt8hK640NJqBvEtWR6ypnDwhD3K-ZIwbDfw-ORHKGKG4WZHvr5bk2jCEcqBu2lEfx3kI3pUQp0xjR-c-lphxQF_CHunezTGFfKUf5dIjnVPMxRWkX0PprypcsE-0Dxc9nTF1MY1u8kjzIRcc6XlCnLZVLD-__aD15z4sIy0ptDEdXQaXMT0k9zo3ZHx0856Sj29efzh722zfn787e7ltvFJQGucc865DYB6EXMtda1rR-ZaZWkbTKeM8yFYBNx64R7VBZN53WmklXb3PKXlx7Tsv7Yg7j1NJbrBzCqNLBxtdsH8rU-jtRdxbpbQ0UlSDpzcGKX5ZMBc7huxxGNyEccmWr5UUIDRsKvrkH_QyLmmq61khmAYhzBoqBdeUr2fNCbvbYTizx_Tt_9KvrY__XOa28Xfc8hduwLEE</recordid><startdate>20140701</startdate><enddate>20140701</enddate><creator>Batura, D</creator><creator>Sahibzada, I</creator><creator>Elkabir, J</creator><creator>Feyisetan, O</creator><creator>Izegbu, V</creator><creator>Hellawell, G</creator><creator>Webster, J</creator><general>BMJ Publishing Group LTD</general><general>Royal College of Surgeons</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>EHMNL</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20140701</creationdate><title>Durability and complications of photoselective vaporisation of the prostate with the 120W high performance system GreenLight™ lithium triborate laser</title><author>Batura, D ; Sahibzada, I ; Elkabir, J ; Feyisetan, O ; Izegbu, V ; Hellawell, G ; Webster, J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c448t-aaa0cafe80c82353db9b2fcb090cae9f49ac83b4819c81ce46ee0ccf74743a003</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adult</topic><topic>Age Distribution</topic><topic>Aged</topic><topic>Antigens</topic><topic>Bladder</topic><topic>Borates</topic><topic>High performance systems</topic><topic>Humans</topic><topic>Laser Therapy - adverse effects</topic><topic>Laser Therapy - methods</topic><topic>Lasers</topic><topic>Length of Stay</topic><topic>Lithium</topic><topic>Lithium Compounds</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Operative Time</topic><topic>Potassium</topic><topic>Prospective Studies</topic><topic>Prostate</topic><topic>Prostatic Hyperplasia - surgery</topic><topic>Retrospective Studies</topic><topic>Sepsis</topic><topic>Surgery</topic><topic>Surgical outcomes</topic><topic>Survival analysis</topic><topic>Transurethral Resection of Prostate - adverse effects</topic><topic>Transurethral Resection of Prostate - methods</topic><topic>Urology</topic><topic>Variables</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Batura, D</creatorcontrib><creatorcontrib>Sahibzada, I</creatorcontrib><creatorcontrib>Elkabir, J</creatorcontrib><creatorcontrib>Feyisetan, O</creatorcontrib><creatorcontrib>Izegbu, V</creatorcontrib><creatorcontrib>Hellawell, G</creatorcontrib><creatorcontrib>Webster, J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Databases</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>UK & Ireland Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Annals of the Royal College of Surgeons of England</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Batura, D</au><au>Sahibzada, I</au><au>Elkabir, J</au><au>Feyisetan, O</au><au>Izegbu, V</au><au>Hellawell, G</au><au>Webster, J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Durability and complications of photoselective vaporisation of the prostate with the 120W high performance system GreenLight™ lithium triborate laser</atitle><jtitle>Annals of the Royal College of Surgeons of England</jtitle><addtitle>Ann R Coll Surg Engl</addtitle><date>2014-07-01</date><risdate>2014</risdate><volume>96</volume><issue>5</issue><spage>359</spage><epage>363</epage><pages>359-363</pages><issn>0035-8843</issn><eissn>1478-7083</eissn><abstract>The aim of this study was to examine the durability of photoselective vaporisation of the prostate (PVP) with the 120W GreenLight HPS(®) laser (American Medical Systems, Minnetonka, MN, US), and to examine the incidence, nature and factors associated with complications from the procedure.
Clinical records of PVP patients were reviewed to compare details between patients who developed complications and those who did not. Kaplan-Meier survival curves were used to assess durability. Cox regression was used to examine associations between complications and perioperative factors.
Successful outcomes were maintained in 84% of 117 patients at the 2-year follow-up appointment. Complication rates were low and comparable with transurethral resection of the prostate (TURP). Complications were developed by 18 patients (15.4%) over a mean follow-up duration of 20.8 months. The most common complications were residual prostate requiring another surgery (5/117, 4.3%) and urethral stricture (4/117, 3.4%). Patients with complications had significantly longer catheterisation duration. Length of hospital stay, lasing energy, pre and postoperative levels of prostate specific antigen (PSA), pre and postoperative maximum flow rate (Qmax), and age at surgery were not found to influence development of complications.
Results from PVP with an HPS(®) laser are durable. Complications are low and compare favourably with TURP. Lasing energy, PSA, Qmax, patient age and length of stay are not associated with development of complications. However, a longer postoperative catheterisation after PVP is associated with development of complications.</abstract><cop>England</cop><pub>BMJ Publishing Group LTD</pub><pmid>24992419</pmid><doi>10.1308/003588414X13946184901047</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Age Distribution Aged Antigens Bladder Borates High performance systems Humans Laser Therapy - adverse effects Laser Therapy - methods Lasers Length of Stay Lithium Lithium Compounds Male Middle Aged Operative Time Potassium Prospective Studies Prostate Prostatic Hyperplasia - surgery Retrospective Studies Sepsis Surgery Surgical outcomes Survival analysis Transurethral Resection of Prostate - adverse effects Transurethral Resection of Prostate - methods Urology Variables |
title | Durability and complications of photoselective vaporisation of the prostate with the 120W high performance system GreenLight™ lithium triborate laser |
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