Cerebral Activity Changes in Different Traditional Chinese Medicine Patterns of Psychogenic Erectile Dysfunction Patients

Background. Pattern differentiation is the foundation of traditional Chinese medicine (TCM) treatment for erectile dysfunction (ED). This study aims to investigate the differences in cerebral activity in ED patients with different TCM patterns. Methods. 27 psychogenic ED patients and 27 healthy subj...

Full description

Saved in:
Bibliographic Details
Published in:Evidence-based complementary and alternative medicine 2015-01, Vol.2015 (2015), p.1-9
Main Authors: Yu, Xujun, Dong, Minghao, Gong, Qiyong, Guo, Jun, Chang, Degui, You, Yaodong, Qin, Wei, Li, Guangsen, Liu, Jixin, Li, Zhengjie, Pan, Junjie, Zhang, Peihai, Liu, Qi, Sun, Jinbo
Format: Article
Language:English
Subjects:
Brain research
Care and treatment
Chinese medicine
Comparative analysis
Diagnosis
Erectile dysfunction
Impotence
Life sciences
Medicine, Chinese
Patients
Penis
Research centers
Teaching hospitals
Ultrasonic imaging
Urology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background. Pattern differentiation is the foundation of traditional Chinese medicine (TCM) treatment for erectile dysfunction (ED). This study aims to investigate the differences in cerebral activity in ED patients with different TCM patterns. Methods. 27 psychogenic ED patients and 27 healthy subjects (HS) were enrolled in this study. Each participant underwent an fMRI scan in resting state. The fractional amplitude of low-frequency fluctuation (fALFF) was used to detect the brain activity changes in ED patients with different patterns. Results. Compared to HS, ED patients showed an increased cerebral activity in bilateral cerebellum, insula, globus pallidus, parahippocampal gyrus, orbitofrontal cortex (OFC), and middle cingulate cortex (MCC). Compared to the patients with liver-qi stagnation and spleen deficiency pattern (LSSDP), the patients with kidney-yang deficiency pattern (KDP) showed an increased activity in bilateral brainstem, cerebellum, hippocampus, and the right insula, thalamus, MCC, and a decreased activity in bilateral putamen, medial frontal gyrus, temporal pole, and the right caudate nucleus, OFC, anterior cingulate cortex, and posterior cingulate cortex (P
ISSN:1741-427X
1741-4288
DOI:10.1155/2015/503536