Loading…
Rhabdomyolysis and exercise-associated hyponatremia in ultra-bikers and ultra-runners
Exercise-associated hyponatremia (EAH), rhabdomyolysis and renal failure appear to be a unique problem in ultra-endurance racers. We investigated the combined occurrence of EAH and rhabdomyolysis in seven different ultra-endurance races and disciplines (i.e. multi-stage mountain biking, 24-h mountai...
Saved in:
| Published in: | Journal of the International Society of Sports Nutrition 2015-06, Vol.12, p.29-29 |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c601t-f84e5a2e05a0c6c2b1f553e59be08c81ae1514e6995d547e2996256610676cf13 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c601t-f84e5a2e05a0c6c2b1f553e59be08c81ae1514e6995d547e2996256610676cf13 |
| container_end_page | 29 |
| container_issue | |
| container_start_page | 29 |
| container_title | Journal of the International Society of Sports Nutrition |
| container_volume | 12 |
| creator | Chlíbková, Daniela Knechtle, Beat Rosemann, Thomas Tomášková, Ivana Novotný, Jan Žákovská, Alena Uher, Tomáš |
| description | Exercise-associated hyponatremia (EAH), rhabdomyolysis and renal failure appear to be a unique problem in ultra-endurance racers.
We investigated the combined occurrence of EAH and rhabdomyolysis in seven different ultra-endurance races and disciplines (i.e. multi-stage mountain biking, 24-h mountain biking, 24-h ultra-running and 100-km ultra-running).
Two (15.4%) ultra-runners (man and woman) from hyponatremic ultra-athletes (n = 13) and four (4%) ultra-runners (four men) from the normonatremic group (n = 100) showed rhabdomyolysis following elevated blood creatine kinase (CK) levels > 10,000 U/L without the development of renal failure and the necessity of a medical treatment. Post-race creatine kinase, plasma and urine creatinine significantly increased, while plasma [Na(+)] and creatine clearance decreased in hyponatremic and normonatremic athletes, respectively. The percentage increase of CK was higher in the hyponatremic compared to the normonatremic group (P |
| doi_str_mv | 10.1186/s12970-015-0091-x |
| format | article |
| fullrecord | <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4480906</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A541516347</galeid><sourcerecordid>A541516347</sourcerecordid><originalsourceid>FETCH-LOGICAL-c601t-f84e5a2e05a0c6c2b1f553e59be08c81ae1514e6995d547e2996256610676cf13</originalsourceid><addsrcrecordid>eNptkl-L1DAUxYMo7h_9AL5IQRB96JqbNmnzsrAsri4sCKv7HNL0dhptkzFpZebbm6HrMgXJQ8LN7xwuh0PIG6AXALX4FIHJiuYUeE6phHz3jJwC5zRnVV08P3qfkLMYf1JalLRiL8kJEwBFTfkpebjvddP6ce-HfbQx067NcIfB2Ii5jtEbqydss36_9U5PAUerM-uyeZiCzhv7C8MiWgZhdi5NXpEXnR4ivn68z8nDzecf11_zu29fbq-v7nIjKEx5V5fINUPKNTXCsAY6zgvkskFamxo0AocShZS85WWFTErBuBBARSVMB8U5uVx8t3MzYmvQpSUGtQ121GGvvLZq_eNsrzb-jyrLmkoqksGHR4Pgf88YJzXaaHAYtEM_RwVCApeFZCyh7xZ0owdU1nU-OZoDrq54mRYVRVkl6uI_VDptSs54h51N85Xg40qQmAl300bPMarb7_dr9v0R26Mepj76YZ6sd3ENwgKa4GMM2D1FAlQdqqOW6qhUHXWojtolzdvjLJ8U_7pS_AXTbb3v</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1691593922</pqid></control><display><type>article</type><title>Rhabdomyolysis and exercise-associated hyponatremia in ultra-bikers and ultra-runners</title><source>EBSCOhost SPORTDiscus with Full Text</source><source>Taylor & Francis Open Access</source><source>Publicly Available Content (ProQuest)</source><source>PubMed Central</source><creator>Chlíbková, Daniela ; Knechtle, Beat ; Rosemann, Thomas ; Tomášková, Ivana ; Novotný, Jan ; Žákovská, Alena ; Uher, Tomáš</creator><creatorcontrib>Chlíbková, Daniela ; Knechtle, Beat ; Rosemann, Thomas ; Tomášková, Ivana ; Novotný, Jan ; Žákovská, Alena ; Uher, Tomáš</creatorcontrib><description>Exercise-associated hyponatremia (EAH), rhabdomyolysis and renal failure appear to be a unique problem in ultra-endurance racers.
We investigated the combined occurrence of EAH and rhabdomyolysis in seven different ultra-endurance races and disciplines (i.e. multi-stage mountain biking, 24-h mountain biking, 24-h ultra-running and 100-km ultra-running).
Two (15.4%) ultra-runners (man and woman) from hyponatremic ultra-athletes (n = 13) and four (4%) ultra-runners (four men) from the normonatremic group (n = 100) showed rhabdomyolysis following elevated blood creatine kinase (CK) levels > 10,000 U/L without the development of renal failure and the necessity of a medical treatment. Post-race creatine kinase, plasma and urine creatinine significantly increased, while plasma [Na(+)] and creatine clearance decreased in hyponatremic and normonatremic athletes, respectively. The percentage increase of CK was higher in the hyponatremic compared to the normonatremic group (P < 0.05). Post-race CK levels were higher in ultra-runners compared to mountain bikers (P < 0.01), in faster normonatremic (P < 0.05) and older and more experienced hyponatremic ultra-athletes (P < 0.05). In all finishers, pre-race plasma [K(+)] was related to post-race CK (P < 0.05).
Hyponatremic ultra-athletes tended to develop exercise-induced rhabdomyolysis more frequently than normonatremic ultra-athletes. Ultra-runners tended to develop rhabdomyolysis more frequently than mountain bikers. We found no association between post-race plasma [Na(+)] and CK concentration in both hypo- and normonatremic ultra-athletes.</description><identifier>ISSN: 1550-2783</identifier><identifier>EISSN: 1550-2783</identifier><identifier>DOI: 10.1186/s12970-015-0091-x</identifier><identifier>PMID: 26113805</identifier><language>eng</language><publisher>United States: BioMed Central Ltd</publisher><subject>Adult ; Athletes ; Bicycling ; Body Mass Index ; Comorbidity ; Creatine ; Creatine kinase ; Creatine Kinase - blood ; Creatinine - urine ; Cyclists ; Development and progression ; Exercise ; Female ; Health aspects ; Humans ; Hyponatremia ; Hyponatremia - blood ; Hyponatremia - urine ; Male ; Middle Aged ; Physiological aspects ; Potassium - blood ; Rhabdomyolysis ; Rhabdomyolysis - blood ; Rhabdomyolysis - urine ; Runners (Sports) ; Running ; Sodium - blood</subject><ispartof>Journal of the International Society of Sports Nutrition, 2015-06, Vol.12, p.29-29</ispartof><rights>COPYRIGHT 2015 BioMed Central Ltd.</rights><rights>Chlíbková et al. 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c601t-f84e5a2e05a0c6c2b1f553e59be08c81ae1514e6995d547e2996256610676cf13</citedby><cites>FETCH-LOGICAL-c601t-f84e5a2e05a0c6c2b1f553e59be08c81ae1514e6995d547e2996256610676cf13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480906/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480906/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,37012,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26113805$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chlíbková, Daniela</creatorcontrib><creatorcontrib>Knechtle, Beat</creatorcontrib><creatorcontrib>Rosemann, Thomas</creatorcontrib><creatorcontrib>Tomášková, Ivana</creatorcontrib><creatorcontrib>Novotný, Jan</creatorcontrib><creatorcontrib>Žákovská, Alena</creatorcontrib><creatorcontrib>Uher, Tomáš</creatorcontrib><title>Rhabdomyolysis and exercise-associated hyponatremia in ultra-bikers and ultra-runners</title><title>Journal of the International Society of Sports Nutrition</title><addtitle>J Int Soc Sports Nutr</addtitle><description>Exercise-associated hyponatremia (EAH), rhabdomyolysis and renal failure appear to be a unique problem in ultra-endurance racers.
We investigated the combined occurrence of EAH and rhabdomyolysis in seven different ultra-endurance races and disciplines (i.e. multi-stage mountain biking, 24-h mountain biking, 24-h ultra-running and 100-km ultra-running).
Two (15.4%) ultra-runners (man and woman) from hyponatremic ultra-athletes (n = 13) and four (4%) ultra-runners (four men) from the normonatremic group (n = 100) showed rhabdomyolysis following elevated blood creatine kinase (CK) levels > 10,000 U/L without the development of renal failure and the necessity of a medical treatment. Post-race creatine kinase, plasma and urine creatinine significantly increased, while plasma [Na(+)] and creatine clearance decreased in hyponatremic and normonatremic athletes, respectively. The percentage increase of CK was higher in the hyponatremic compared to the normonatremic group (P < 0.05). Post-race CK levels were higher in ultra-runners compared to mountain bikers (P < 0.01), in faster normonatremic (P < 0.05) and older and more experienced hyponatremic ultra-athletes (P < 0.05). In all finishers, pre-race plasma [K(+)] was related to post-race CK (P < 0.05).
Hyponatremic ultra-athletes tended to develop exercise-induced rhabdomyolysis more frequently than normonatremic ultra-athletes. Ultra-runners tended to develop rhabdomyolysis more frequently than mountain bikers. We found no association between post-race plasma [Na(+)] and CK concentration in both hypo- and normonatremic ultra-athletes.</description><subject>Adult</subject><subject>Athletes</subject><subject>Bicycling</subject><subject>Body Mass Index</subject><subject>Comorbidity</subject><subject>Creatine</subject><subject>Creatine kinase</subject><subject>Creatine Kinase - blood</subject><subject>Creatinine - urine</subject><subject>Cyclists</subject><subject>Development and progression</subject><subject>Exercise</subject><subject>Female</subject><subject>Health aspects</subject><subject>Humans</subject><subject>Hyponatremia</subject><subject>Hyponatremia - blood</subject><subject>Hyponatremia - urine</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Physiological aspects</subject><subject>Potassium - blood</subject><subject>Rhabdomyolysis</subject><subject>Rhabdomyolysis - blood</subject><subject>Rhabdomyolysis - urine</subject><subject>Runners (Sports)</subject><subject>Running</subject><subject>Sodium - blood</subject><issn>1550-2783</issn><issn>1550-2783</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNptkl-L1DAUxYMo7h_9AL5IQRB96JqbNmnzsrAsri4sCKv7HNL0dhptkzFpZebbm6HrMgXJQ8LN7xwuh0PIG6AXALX4FIHJiuYUeE6phHz3jJwC5zRnVV08P3qfkLMYf1JalLRiL8kJEwBFTfkpebjvddP6ce-HfbQx067NcIfB2Ii5jtEbqydss36_9U5PAUerM-uyeZiCzhv7C8MiWgZhdi5NXpEXnR4ivn68z8nDzecf11_zu29fbq-v7nIjKEx5V5fINUPKNTXCsAY6zgvkskFamxo0AocShZS85WWFTErBuBBARSVMB8U5uVx8t3MzYmvQpSUGtQ121GGvvLZq_eNsrzb-jyrLmkoqksGHR4Pgf88YJzXaaHAYtEM_RwVCApeFZCyh7xZ0owdU1nU-OZoDrq54mRYVRVkl6uI_VDptSs54h51N85Xg40qQmAl300bPMarb7_dr9v0R26Mepj76YZ6sd3ENwgKa4GMM2D1FAlQdqqOW6qhUHXWojtolzdvjLJ8U_7pS_AXTbb3v</recordid><startdate>20150625</startdate><enddate>20150625</enddate><creator>Chlíbková, Daniela</creator><creator>Knechtle, Beat</creator><creator>Rosemann, Thomas</creator><creator>Tomášková, Ivana</creator><creator>Novotný, Jan</creator><creator>Žákovská, Alena</creator><creator>Uher, Tomáš</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>ISR</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20150625</creationdate><title>Rhabdomyolysis and exercise-associated hyponatremia in ultra-bikers and ultra-runners</title><author>Chlíbková, Daniela ; Knechtle, Beat ; Rosemann, Thomas ; Tomášková, Ivana ; Novotný, Jan ; Žákovská, Alena ; Uher, Tomáš</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c601t-f84e5a2e05a0c6c2b1f553e59be08c81ae1514e6995d547e2996256610676cf13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Athletes</topic><topic>Bicycling</topic><topic>Body Mass Index</topic><topic>Comorbidity</topic><topic>Creatine</topic><topic>Creatine kinase</topic><topic>Creatine Kinase - blood</topic><topic>Creatinine - urine</topic><topic>Cyclists</topic><topic>Development and progression</topic><topic>Exercise</topic><topic>Female</topic><topic>Health aspects</topic><topic>Humans</topic><topic>Hyponatremia</topic><topic>Hyponatremia - blood</topic><topic>Hyponatremia - urine</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Physiological aspects</topic><topic>Potassium - blood</topic><topic>Rhabdomyolysis</topic><topic>Rhabdomyolysis - blood</topic><topic>Rhabdomyolysis - urine</topic><topic>Runners (Sports)</topic><topic>Running</topic><topic>Sodium - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chlíbková, Daniela</creatorcontrib><creatorcontrib>Knechtle, Beat</creatorcontrib><creatorcontrib>Rosemann, Thomas</creatorcontrib><creatorcontrib>Tomášková, Ivana</creatorcontrib><creatorcontrib>Novotný, Jan</creatorcontrib><creatorcontrib>Žákovská, Alena</creatorcontrib><creatorcontrib>Uher, Tomáš</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Science</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of the International Society of Sports Nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chlíbková, Daniela</au><au>Knechtle, Beat</au><au>Rosemann, Thomas</au><au>Tomášková, Ivana</au><au>Novotný, Jan</au><au>Žákovská, Alena</au><au>Uher, Tomáš</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Rhabdomyolysis and exercise-associated hyponatremia in ultra-bikers and ultra-runners</atitle><jtitle>Journal of the International Society of Sports Nutrition</jtitle><addtitle>J Int Soc Sports Nutr</addtitle><date>2015-06-25</date><risdate>2015</risdate><volume>12</volume><spage>29</spage><epage>29</epage><pages>29-29</pages><issn>1550-2783</issn><eissn>1550-2783</eissn><abstract>Exercise-associated hyponatremia (EAH), rhabdomyolysis and renal failure appear to be a unique problem in ultra-endurance racers.
We investigated the combined occurrence of EAH and rhabdomyolysis in seven different ultra-endurance races and disciplines (i.e. multi-stage mountain biking, 24-h mountain biking, 24-h ultra-running and 100-km ultra-running).
Two (15.4%) ultra-runners (man and woman) from hyponatremic ultra-athletes (n = 13) and four (4%) ultra-runners (four men) from the normonatremic group (n = 100) showed rhabdomyolysis following elevated blood creatine kinase (CK) levels > 10,000 U/L without the development of renal failure and the necessity of a medical treatment. Post-race creatine kinase, plasma and urine creatinine significantly increased, while plasma [Na(+)] and creatine clearance decreased in hyponatremic and normonatremic athletes, respectively. The percentage increase of CK was higher in the hyponatremic compared to the normonatremic group (P < 0.05). Post-race CK levels were higher in ultra-runners compared to mountain bikers (P < 0.01), in faster normonatremic (P < 0.05) and older and more experienced hyponatremic ultra-athletes (P < 0.05). In all finishers, pre-race plasma [K(+)] was related to post-race CK (P < 0.05).
Hyponatremic ultra-athletes tended to develop exercise-induced rhabdomyolysis more frequently than normonatremic ultra-athletes. Ultra-runners tended to develop rhabdomyolysis more frequently than mountain bikers. We found no association between post-race plasma [Na(+)] and CK concentration in both hypo- and normonatremic ultra-athletes.</abstract><cop>United States</cop><pub>BioMed Central Ltd</pub><pmid>26113805</pmid><doi>10.1186/s12970-015-0091-x</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1550-2783 |
| ispartof | Journal of the International Society of Sports Nutrition, 2015-06, Vol.12, p.29-29 |
| issn | 1550-2783 1550-2783 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4480906 |
| source | EBSCOhost SPORTDiscus with Full Text; Taylor & Francis Open Access; Publicly Available Content (ProQuest); PubMed Central |
| subjects | Adult Athletes Bicycling Body Mass Index Comorbidity Creatine Creatine kinase Creatine Kinase - blood Creatinine - urine Cyclists Development and progression Exercise Female Health aspects Humans Hyponatremia Hyponatremia - blood Hyponatremia - urine Male Middle Aged Physiological aspects Potassium - blood Rhabdomyolysis Rhabdomyolysis - blood Rhabdomyolysis - urine Runners (Sports) Running Sodium - blood |
| title | Rhabdomyolysis and exercise-associated hyponatremia in ultra-bikers and ultra-runners |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T03%3A57%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Rhabdomyolysis%20and%20exercise-associated%20hyponatremia%20in%20ultra-bikers%20and%20ultra-runners&rft.jtitle=Journal%20of%20the%20International%20Society%20of%20Sports%20Nutrition&rft.au=Chl%C3%ADbkov%C3%A1,%20Daniela&rft.date=2015-06-25&rft.volume=12&rft.spage=29&rft.epage=29&rft.pages=29-29&rft.issn=1550-2783&rft.eissn=1550-2783&rft_id=info:doi/10.1186/s12970-015-0091-x&rft_dat=%3Cgale_pubme%3EA541516347%3C/gale_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c601t-f84e5a2e05a0c6c2b1f553e59be08c81ae1514e6995d547e2996256610676cf13%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1691593922&rft_id=info:pmid/26113805&rft_galeid=A541516347&rfr_iscdi=true |