Pancreatic mucinous cystic neoplasm in a transgender patient

Cystic pancreatic lesions are increasingly more frequent detected clinical entities. Mucinous cystic neoplasm (MCN) is a hormone-related pancreatic tumor (HRTP) with a strong predominance in young and middle-aged females. Here, we present the case of a 31-year-old surgically transgendered female-to-...

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Bibliographic Details
Published in:World journal of surgical oncology 2015-06, Vol.13 (1), p.205-205, Article 205
Main Authors: Foster, Deshka, Shaikh, Mohammad F, Gleeson, Elizabeth, Babcock, Blake D, Lin, Jianping, Ownbey, Robert T, Hysell, Mark E, Ringold, Daniel, Bowne, Wilbur B
Format: Article
Language:English
Subjects:
Adult
Care and treatment
Case Report
Cystadenoma, Mucinous - pathology
Cystadenoma, Mucinous - surgery
Female
Health aspects
Hormone therapy
Humans
Male
Pancreatectomy
Pancreatic cancer
Pancreatic Neoplasms - pathology
Pancreatic Neoplasms - surgery
Pancreatitis
Patient outcomes
Physiological aspects
Prognosis
Testosterone
Transgender people
Transgender Persons
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Summary:Cystic pancreatic lesions are increasingly more frequent detected clinical entities. Mucinous cystic neoplasm (MCN) is a hormone-related pancreatic tumor (HRTP) with a strong predominance in young and middle-aged females. Here, we present the case of a 31-year-old surgically transgendered female-to-male patient with a history of alcoholic pancreatitis, on chronic testosterone therapy. He was found to have a pancreatic MCN and underwent distal pancreatectomy and splenectomy. To our knowledge, this is the first reported case of a transgender patient with a history of hormone replacement therapy (HRT) and pancreatic MCN. We consider possible mechanisms for the pathogenesis to explain this patient's neoplasm.
ISSN:1477-7819
1477-7819
DOI:10.1186/s12957-015-0620-8