Complete resection of isolated hepatic metastatic uveal melanoma with a notably long disease-free period: A case report and review of the literature

Although uveal melanoma frequently metastasizes to the liver, cases with a large solitary lesion with spontaneous intratumoral hemorrhage and necrosis are rarely encountered. Here, we report a case of metastatic hepatic melanoma that occurred in a 45-year-old Chinese male. The patient complained of...

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Bibliographic Details
Published in:Oncology letters 2015-07, Vol.10 (1), p.196-200
Main Authors: LIN, SHENGZHANG, WAN, DALONG, CHEN, HAIYONG, CHEN, KANGJIE, ZHENG, SHUSEN
Format: Article
Language:English
Subjects:
Abdomen
Care and treatment
Case reports
Case studies
CT imaging
Diagnosis
Excision (Surgery)
Health aspects
hepatic metastasis
Hospitals
intratumoral hemorrhage
large solitary lesion
Liver cancer
long disease-free period
Medical imaging
Medical prognosis
Melanoma
Metastasis
NMR
Nuclear magnetic resonance
Oncology
Patients
PET imaging
Proteins
Surgeons
Surgery
uveal melanoma
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Summary:Although uveal melanoma frequently metastasizes to the liver, cases with a large solitary lesion with spontaneous intratumoral hemorrhage and necrosis are rarely encountered. Here, we report a case of metastatic hepatic melanoma that occurred in a 45-year-old Chinese male. The patient complained of the feeling of a full stomach for a month. Ten years earlier, the patient had undergone left ocular enucleation and artificial eye implantation at a different hospital. Postoperative pathology revealed choroidal melanoma without intrascleral or vascular involvement. Abdominal magnetic resonance imaging and computed tomography scan revealed a solitary lesion measuring 12 cm in diameter. A whole-body F-18-fluoro-2-deoxyglucose (FDG) positron emission tomography/computed tomography scan demonstrated a large solitary nodule with increased FDG uptake. Computed tomography angiography revealed that the huge mass had partially ruptured and was bleeding spontaneously. For diagnostic and therapeutic purposes, right hepatectomy was performed and histological examination revealed that the tumor was metastatic melanoma.
ISSN:1792-1074
1792-1082
DOI:10.3892/ol.2015.3217