Fast-track laparoscopic surgery: A better option for treating colorectal cancer than conventional laparoscopic surgery

Fast-track surgery (FTS), a multimodal rehabilitation technique, has been recommended as surgical therapy for colorectal cancer. The objective of the present study was to compare the outcomes of FTS and conventional laparoscopic surgery. This study was a blinded randomized trial. A total of 70 patie...

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Published in:Oncology letters 2015-07, Vol.10 (1), p.443-448
Main Authors: TAUPYK, YERLAN, CAO, XUEYUAN, ZHAO, YINQUAN, WANG, CHAO, WANG, QUAN
Format: Article
Language:English
Subjects:
Analgesics
Anesthesia
Antibiotics
Cancer
Care and treatment
Clinical trials
Colorectal cancer
Comparative analysis
Disease
fast-track surgery
Fasting
Hospitals
Infections
Laparoscopic surgery
Laparoscopy
Metastasis
Nutrition research
Oncology
Oncology, Experimental
Patients
Proteins
randomized trial
Standard deviation
Surgery
Surgical outcomes
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creator TAUPYK, YERLAN
CAO, XUEYUAN
ZHAO, YINQUAN
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WANG, QUAN
description Fast-track surgery (FTS), a multimodal rehabilitation technique, has been recommended as surgical therapy for colorectal cancer. The objective of the present study was to compare the outcomes of FTS and conventional laparoscopic surgery. This study was a blinded randomized trial. A total of 70 patients with colorectal cancer were divided into two groups and underwent laparoscopic colorectal resection. The FTS group consisted of 31 patients and the control group consisted of 39 patients. Protocols for the treatment of the FTS group included skipping pre-operative mechanical bowel preparation, early restoration of diet and early post-operative ambulation. Outcome measures, length of hospital stay, post-operative surgical stress response [C-reactive protein (CRP)] and post-operative complications were compared between the two groups. The average length of total hospital stay for the FTS and the control groups was 5.9±0.8 and 10.9±1.3 days, respectively (P
doi_str_mv 10.3892/ol.2015.3166
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The objective of the present study was to compare the outcomes of FTS and conventional laparoscopic surgery. This study was a blinded randomized trial. A total of 70 patients with colorectal cancer were divided into two groups and underwent laparoscopic colorectal resection. The FTS group consisted of 31 patients and the control group consisted of 39 patients. Protocols for the treatment of the FTS group included skipping pre-operative mechanical bowel preparation, early restoration of diet and early post-operative ambulation. Outcome measures, length of hospital stay, post-operative surgical stress response [C-reactive protein (CRP)] and post-operative complications were compared between the two groups. The average length of total hospital stay for the FTS and the control groups was 5.9±0.8 and 10.9±1.3 days, respectively (P<0.05), and the length of post-operative hospital stay for the FTS and control group was 4.3±0.8 and 8.0±1.1 days, respectively. (P<0.05) First flatus time for the FTS and control groups was 1.6±0.8 and 2.5±0.9 days, respectively (P<0.05). Defecation time for the FTS and control groups was 2.2±0.7 and 4.5±0.7 days, respectively (P<0.05). The time to restoration of a solid diet also showed a significant difference between the FTS and control groups (1.1±0.3 vs. 3.6±0.9 days; P<0.05). Following surgery, due to post-operative surgical stress, the two groups CRP levels increased significantly, but the levels of the FTS group were lower than those of the conventional control group (P<0.05). There was no difference in post-operative complications between the FTS and control groups. This study confirms that FTS shortens hospital stay and accelerates the recovery of bowel function without increase of post-operative complications. 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subjects Analgesics
Anesthesia
Antibiotics
Cancer
Care and treatment
Clinical trials
Colorectal cancer
Comparative analysis
Disease
fast-track surgery
Fasting
Hospitals
Infections
Laparoscopic surgery
Laparoscopy
Metastasis
Nutrition research
Oncology
Oncology, Experimental
Patients
Proteins
randomized trial
Standard deviation
Surgery
Surgical outcomes
title Fast-track laparoscopic surgery: A better option for treating colorectal cancer than conventional laparoscopic surgery
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