Topical Oxygen for Chronic Wounds: A PRO/CON Debate

Abstract The role of oxygen in wound healing is universally accepted and does not require any further evidence; however the controversy as to whether oxygen delivery systems have the potential to improve wound healing remains to be concluded. Topical oxygen treatment (TOT) involves the delivery of 1...

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Bibliographic Details
Published in:The journal of the American College of Clinical Wound Specialists 2013-12, Vol.5 (3), p.61-65
Main Authors: Mutluoglu, Mesut, MD, Cakkalkurt, Aslican, MD, Uzun, Gunalp, MD, Aktas, Samil, MD
Format: Article
Language:English
Subjects:
Critical Care
Hyperbaric oxygen
Internal Medicine
Oxidative stress
Reactive oxygen species
Review
Topical oxygen
Wound healing
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Summary:Abstract The role of oxygen in wound healing is universally accepted and does not require any further evidence; however the controversy as to whether oxygen delivery systems have the potential to improve wound healing remains to be concluded. Topical oxygen treatment (TOT) involves the delivery of 100% oxygen for a mean of 90 min, once a day at an atmospheric pressure slightly above 1 atm abs. The use of TOT gained increasing interest recently. The current manuscript will summarize the pros and cons of TOT in the view of the available literature.
ISSN:2213-5103
2213-5103
DOI:10.1016/j.jccw.2014.12.003