Prognostic models for alcoholic hepatitis

Alcoholic hepatitis (AH) is caused by acute inflammation of the liver in patients that consume excessive amounts of alcohol, usually in a background of cirrhosis. AH can range from mild to severe, life threatening disease with a high rate of short and long-term mortality. Prognostic models have been...

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Bibliographic Details
Published in:Biomarker research 2015-07, Vol.3 (1), p.20-20, Article 20
Main Authors: Rahimi, Erik, Pan, Jen-Jung
Format: Article
Language:English
Subjects:
Analysis
Diagnosis
Drug therapy
Health aspects
Hepatitis
Liver
Liver cirrhosis
Mortality
Review
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Summary:Alcoholic hepatitis (AH) is caused by acute inflammation of the liver in patients that consume excessive amounts of alcohol, usually in a background of cirrhosis. AH can range from mild to severe, life threatening disease with a high rate of short and long-term mortality. Prognostic models have been used to estimate mortality in order to identify those that may benefit from corticosteroids or pentoxifylline. This review focuses on the different prognostic models proposed. While limitations of the prognostic models exist, combining models may be beneficial in order to identify responders to therapy versus non-responders.
ISSN:2050-7771
2050-7771
DOI:10.1186/s40364-015-0046-z