Hypoparathyroidism in pregnancy

Hypoparathyroidism is an uncommon endocrine deficiency characterised by low serum calcium, absent or inappropriately low parathyroid hormone and normal or high serum phosphorus levels. Parathyroid hormone is essential for calcium homoeostasis. Pregnancy and lactation are known for increased calcium...

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Bibliographic Details
Published in:BMJ case reports 2015-07, Vol.2015, p.bcr2015210228
Main Authors: Shah, Krupa Hitesh, Bhat, Shashikala, Shetty, Seema, Umakanth, Shashikiran
Format: Article
Language:English
Subjects:
Adult
Asia
Breast Feeding
Breastfeeding & lactation
Calcium - blood
Drug dosages
Female
Hormones
Humans
Hypocalcemia - complications
Hypoparathyroidism - blood
Hypoparathyroidism - complications
Indian Sub-Continent
Lactation - metabolism
Parathyroid Hormone - blood
Physiology
Potassium
Pregnancy
Pregnancy Complications - blood
Reminder of Important Clinical Lesson
Thyroid gland
Vitamin D
Weaning
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Summary:Hypoparathyroidism is an uncommon endocrine deficiency characterised by low serum calcium, absent or inappropriately low parathyroid hormone and normal or high serum phosphorus levels. Parathyroid hormone is essential for calcium homoeostasis. Pregnancy and lactation are known for increased calcium requirement. They cause calcium stress as well as alter its metabolism. Hence, many abnormalities are expected in hypoparathyroidism during pregnancy and lactation. We report a case of pregnancy in postsurgical hypoparathyroidism, which is rarely encountered in antenatal clinics. We describe our clinical, biochemical and therapeutic experience of pregnancy and lactation in this patient with hypoparathyroidism.
ISSN:1757-790X
1757-790X
DOI:10.1136/bcr-2015-210228