Efficacy of intravenous immunoglobulins in a patient with systemic lupus erythematosus presenting with Stevens-Johnson syndrome

Both drugs were discontinued and she improved within 4-7 days. Since hydroxychloroquine is associated with more hypersensitivity reactions than azathioprine, the latter was reintroduced, but 2 days later, the patient developed severe recurrent skin lesions ( figure 1 A-C).

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Bibliographic Details
Published in:BMJ case reports 2015-07, Vol.2015, p.bcr2015211157
Main Authors: Vazquez-Sanabria, Irma L, Mercado-Seda, Rogelio, Varela-Rosario, Noemi, Vila, Luis M
Format: Article
Language:English
Subjects:
Adult
Azathioprine - adverse effects
Azathioprine - therapeutic use
Edema
Female
Humans
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Immunoglobulins
Immunoglobulins, Intravenous - administration & dosage
Immunoglobulins, Intravenous - therapeutic use
Immunosuppressive Agents - adverse effects
Immunosuppressive Agents - therapeutic use
Lupus
Lupus Erythematosus, Systemic - drug therapy
Other
South/Central America
Stevens-Johnson Syndrome - drug therapy
Stevens-Johnson Syndrome - etiology
Treatment Outcome
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Description
Summary:Both drugs were discontinued and she improved within 4-7 days. Since hydroxychloroquine is associated with more hypersensitivity reactions than azathioprine, the latter was reintroduced, but 2 days later, the patient developed severe recurrent skin lesions ( figure 1 A-C).
ISSN:1757-790X
1757-790X
DOI:10.1136/bcr-2015-211157