Assessment of dipyridamole stress echocardiography for risk stratification of diabetic patients

Despite advances in medical therapy, cardiovascular disease, mainly coronary artery disease (CAD), remains the leading cause of mortality among patients with diabetes mellitus (DM). The objective of the present study was to assess the effectiveness of dipyridamole stress echocardiography in identify...

Full description

Saved in:
Bibliographic Details
Published in:Cardiovascular ultrasound 2015-07, Vol.13 (1), p.35-35, Article 35
Main Authors: Baroncini, Liz Andréa Villela, Borsoi, Rafael, Vidal, Maria Eugênia Bégué, Valente, Nathália Julim, Veloso, Juliana, Pecoits Filho, Roberto
Format: Article
Language:English
Subjects:
Brazil - epidemiology
Comorbidity
Coronary Artery Disease - diagnostic imaging
Coronary Artery Disease - mortality
Diabetes Complications - diagnostic imaging
Diabetes Complications - mortality
Dipyridamole
Echocardiography, Stress - statistics & numerical data
Exercise Test
Female
Humans
Incidence
Male
Middle Aged
Prognosis
Reproducibility of Results
Risk Assessment - methods
Sensitivity and Specificity
Survival Analysis
Vasodilator Agents
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c466t-8957039c86407daafda79e163659e5efd4c8c2ca871f778887eef1cc40125ac63
cites cdi_FETCH-LOGICAL-c466t-8957039c86407daafda79e163659e5efd4c8c2ca871f778887eef1cc40125ac63
container_end_page 35
container_issue 1
container_start_page 35
container_title Cardiovascular ultrasound
container_volume 13
creator Baroncini, Liz Andréa Villela
Borsoi, Rafael
Vidal, Maria Eugênia Bégué
Valente, Nathália Julim
Veloso, Juliana
Pecoits Filho, Roberto
description Despite advances in medical therapy, cardiovascular disease, mainly coronary artery disease (CAD), remains the leading cause of mortality among patients with diabetes mellitus (DM). The objective of the present study was to assess the effectiveness of dipyridamole stress echocardiography in identify diabetic patients at high risk for cardiovascular events. Dipyridamole stress echocardiography was administered to 483 diabetic patients (294 women; mean age 63.41 ± 11.28 years) between July 2006 and December 2012. Follow-up data were available for 264 patients (163 women; mean age 64.3 ± 10.5 years): 250 with a negative stress echocardiography and 14 with a positive stress echo. During a mean follow-up time of 18 ± 14 months, a cardiovascular event occurred in 18 (6.8%) patients, 12 (4.8%) in patients with a negative stress echo (n = 250) during a mean follow-up period of 20 ± 16 months and 6 (42%) in patients with positive stress echo (n = 14) during a mean follow-up of 13 ± 13 months. The positive and negative predictive values of stress echocardiography were 42% and 96% respectively. The accuracy value was 92%. A Cox regression model showed that CAD (hazard ratio [HR] 5.4, 95% confidence interval [CI] 1.9-15.4; p = 0.002) and positive stress echocardiography (HR 7.1, 95% CI 2.5-20.5; p 
doi_str_mv 10.1186/s12947-015-0030-7
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4515011</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1699491356</sourcerecordid><originalsourceid>FETCH-LOGICAL-c466t-8957039c86407daafda79e163659e5efd4c8c2ca871f778887eef1cc40125ac63</originalsourceid><addsrcrecordid>eNpVkctOwzAQRS0EoqXwAWxQlmwCHifxY4NUVbykSmxgbbmO3RqSONgpUv-eRClV2YxHM3PvtXQQugZ8B8DpfQQicpZiKFKMM5yyEzSFnNGUAcGnR_0EXcT4iTEhkPFzNCGUYAGYTJGcx2hirE3TJd4mpWt3wZWq9pVJYhf6VWL0xmsVSufXQbWbXWJ9SIKLX8OB6px1uq--GfVqZTqnk7Yf9Z7xEp1ZVUVztX9n6OPp8X3xki7fnl8X82Wqc0q7lIuC4UxoTnPMSqVsqZgwQDNaCFMYW-aaa6IVZ2AZ45wzYyxonWMghdI0m6GH0bfdrmpT6j47qEq2wdUq7KRXTv7fNG4j1_5H5gUUGKA3uN0bBP-9NbGTtYvaVJVqjN9GCVSIXEBWDFkwnurgYwzGHmIAywGMHMHIHowcwEjWa26O_3dQ_JHIfgH7wYx1</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1699491356</pqid></control><display><type>article</type><title>Assessment of dipyridamole stress echocardiography for risk stratification of diabetic patients</title><source>Publicly Available Content Database</source><source>PubMed Central</source><creator>Baroncini, Liz Andréa Villela ; Borsoi, Rafael ; Vidal, Maria Eugênia Bégué ; Valente, Nathália Julim ; Veloso, Juliana ; Pecoits Filho, Roberto</creator><creatorcontrib>Baroncini, Liz Andréa Villela ; Borsoi, Rafael ; Vidal, Maria Eugênia Bégué ; Valente, Nathália Julim ; Veloso, Juliana ; Pecoits Filho, Roberto</creatorcontrib><description>Despite advances in medical therapy, cardiovascular disease, mainly coronary artery disease (CAD), remains the leading cause of mortality among patients with diabetes mellitus (DM). The objective of the present study was to assess the effectiveness of dipyridamole stress echocardiography in identify diabetic patients at high risk for cardiovascular events. Dipyridamole stress echocardiography was administered to 483 diabetic patients (294 women; mean age 63.41 ± 11.28 years) between July 2006 and December 2012. Follow-up data were available for 264 patients (163 women; mean age 64.3 ± 10.5 years): 250 with a negative stress echocardiography and 14 with a positive stress echo. During a mean follow-up time of 18 ± 14 months, a cardiovascular event occurred in 18 (6.8%) patients, 12 (4.8%) in patients with a negative stress echo (n = 250) during a mean follow-up period of 20 ± 16 months and 6 (42%) in patients with positive stress echo (n = 14) during a mean follow-up of 13 ± 13 months. The positive and negative predictive values of stress echocardiography were 42% and 96% respectively. The accuracy value was 92%. A Cox regression model showed that CAD (hazard ratio [HR] 5.4, 95% confidence interval [CI] 1.9-15.4; p = 0.002) and positive stress echocardiography (HR 7.1, 95% CI 2.5-20.5; p &lt; 0.001) were significant predictors of cardiovascular events. For patients with diabetes, a negative dipyridamole stress echocardiogram predicts favorable outcome during the first year of follow-up. A new stress imaging test should be done after 12 months in diabetic patients.</description><identifier>ISSN: 1476-7120</identifier><identifier>EISSN: 1476-7120</identifier><identifier>DOI: 10.1186/s12947-015-0030-7</identifier><identifier>PMID: 26209102</identifier><language>eng</language><publisher>England: BioMed Central</publisher><subject>Brazil - epidemiology ; Comorbidity ; Coronary Artery Disease - diagnostic imaging ; Coronary Artery Disease - mortality ; Diabetes Complications - diagnostic imaging ; Diabetes Complications - mortality ; Dipyridamole ; Echocardiography, Stress - statistics &amp; numerical data ; Exercise Test ; Female ; Humans ; Incidence ; Male ; Middle Aged ; Prognosis ; Reproducibility of Results ; Risk Assessment - methods ; Sensitivity and Specificity ; Survival Analysis ; Vasodilator Agents</subject><ispartof>Cardiovascular ultrasound, 2015-07, Vol.13 (1), p.35-35, Article 35</ispartof><rights>Baroncini et al. 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c466t-8957039c86407daafda79e163659e5efd4c8c2ca871f778887eef1cc40125ac63</citedby><cites>FETCH-LOGICAL-c466t-8957039c86407daafda79e163659e5efd4c8c2ca871f778887eef1cc40125ac63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515011/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515011/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,37013,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26209102$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Baroncini, Liz Andréa Villela</creatorcontrib><creatorcontrib>Borsoi, Rafael</creatorcontrib><creatorcontrib>Vidal, Maria Eugênia Bégué</creatorcontrib><creatorcontrib>Valente, Nathália Julim</creatorcontrib><creatorcontrib>Veloso, Juliana</creatorcontrib><creatorcontrib>Pecoits Filho, Roberto</creatorcontrib><title>Assessment of dipyridamole stress echocardiography for risk stratification of diabetic patients</title><title>Cardiovascular ultrasound</title><addtitle>Cardiovasc Ultrasound</addtitle><description>Despite advances in medical therapy, cardiovascular disease, mainly coronary artery disease (CAD), remains the leading cause of mortality among patients with diabetes mellitus (DM). The objective of the present study was to assess the effectiveness of dipyridamole stress echocardiography in identify diabetic patients at high risk for cardiovascular events. Dipyridamole stress echocardiography was administered to 483 diabetic patients (294 women; mean age 63.41 ± 11.28 years) between July 2006 and December 2012. Follow-up data were available for 264 patients (163 women; mean age 64.3 ± 10.5 years): 250 with a negative stress echocardiography and 14 with a positive stress echo. During a mean follow-up time of 18 ± 14 months, a cardiovascular event occurred in 18 (6.8%) patients, 12 (4.8%) in patients with a negative stress echo (n = 250) during a mean follow-up period of 20 ± 16 months and 6 (42%) in patients with positive stress echo (n = 14) during a mean follow-up of 13 ± 13 months. The positive and negative predictive values of stress echocardiography were 42% and 96% respectively. The accuracy value was 92%. A Cox regression model showed that CAD (hazard ratio [HR] 5.4, 95% confidence interval [CI] 1.9-15.4; p = 0.002) and positive stress echocardiography (HR 7.1, 95% CI 2.5-20.5; p &lt; 0.001) were significant predictors of cardiovascular events. For patients with diabetes, a negative dipyridamole stress echocardiogram predicts favorable outcome during the first year of follow-up. A new stress imaging test should be done after 12 months in diabetic patients.</description><subject>Brazil - epidemiology</subject><subject>Comorbidity</subject><subject>Coronary Artery Disease - diagnostic imaging</subject><subject>Coronary Artery Disease - mortality</subject><subject>Diabetes Complications - diagnostic imaging</subject><subject>Diabetes Complications - mortality</subject><subject>Dipyridamole</subject><subject>Echocardiography, Stress - statistics &amp; numerical data</subject><subject>Exercise Test</subject><subject>Female</subject><subject>Humans</subject><subject>Incidence</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Prognosis</subject><subject>Reproducibility of Results</subject><subject>Risk Assessment - methods</subject><subject>Sensitivity and Specificity</subject><subject>Survival Analysis</subject><subject>Vasodilator Agents</subject><issn>1476-7120</issn><issn>1476-7120</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNpVkctOwzAQRS0EoqXwAWxQlmwCHifxY4NUVbykSmxgbbmO3RqSONgpUv-eRClV2YxHM3PvtXQQugZ8B8DpfQQicpZiKFKMM5yyEzSFnNGUAcGnR_0EXcT4iTEhkPFzNCGUYAGYTJGcx2hirE3TJd4mpWt3wZWq9pVJYhf6VWL0xmsVSufXQbWbXWJ9SIKLX8OB6px1uq--GfVqZTqnk7Yf9Z7xEp1ZVUVztX9n6OPp8X3xki7fnl8X82Wqc0q7lIuC4UxoTnPMSqVsqZgwQDNaCFMYW-aaa6IVZ2AZ45wzYyxonWMghdI0m6GH0bfdrmpT6j47qEq2wdUq7KRXTv7fNG4j1_5H5gUUGKA3uN0bBP-9NbGTtYvaVJVqjN9GCVSIXEBWDFkwnurgYwzGHmIAywGMHMHIHowcwEjWa26O_3dQ_JHIfgH7wYx1</recordid><startdate>20150725</startdate><enddate>20150725</enddate><creator>Baroncini, Liz Andréa Villela</creator><creator>Borsoi, Rafael</creator><creator>Vidal, Maria Eugênia Bégué</creator><creator>Valente, Nathália Julim</creator><creator>Veloso, Juliana</creator><creator>Pecoits Filho, Roberto</creator><general>BioMed Central</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20150725</creationdate><title>Assessment of dipyridamole stress echocardiography for risk stratification of diabetic patients</title><author>Baroncini, Liz Andréa Villela ; Borsoi, Rafael ; Vidal, Maria Eugênia Bégué ; Valente, Nathália Julim ; Veloso, Juliana ; Pecoits Filho, Roberto</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c466t-8957039c86407daafda79e163659e5efd4c8c2ca871f778887eef1cc40125ac63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Brazil - epidemiology</topic><topic>Comorbidity</topic><topic>Coronary Artery Disease - diagnostic imaging</topic><topic>Coronary Artery Disease - mortality</topic><topic>Diabetes Complications - diagnostic imaging</topic><topic>Diabetes Complications - mortality</topic><topic>Dipyridamole</topic><topic>Echocardiography, Stress - statistics &amp; numerical data</topic><topic>Exercise Test</topic><topic>Female</topic><topic>Humans</topic><topic>Incidence</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Prognosis</topic><topic>Reproducibility of Results</topic><topic>Risk Assessment - methods</topic><topic>Sensitivity and Specificity</topic><topic>Survival Analysis</topic><topic>Vasodilator Agents</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Baroncini, Liz Andréa Villela</creatorcontrib><creatorcontrib>Borsoi, Rafael</creatorcontrib><creatorcontrib>Vidal, Maria Eugênia Bégué</creatorcontrib><creatorcontrib>Valente, Nathália Julim</creatorcontrib><creatorcontrib>Veloso, Juliana</creatorcontrib><creatorcontrib>Pecoits Filho, Roberto</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Cardiovascular ultrasound</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Baroncini, Liz Andréa Villela</au><au>Borsoi, Rafael</au><au>Vidal, Maria Eugênia Bégué</au><au>Valente, Nathália Julim</au><au>Veloso, Juliana</au><au>Pecoits Filho, Roberto</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Assessment of dipyridamole stress echocardiography for risk stratification of diabetic patients</atitle><jtitle>Cardiovascular ultrasound</jtitle><addtitle>Cardiovasc Ultrasound</addtitle><date>2015-07-25</date><risdate>2015</risdate><volume>13</volume><issue>1</issue><spage>35</spage><epage>35</epage><pages>35-35</pages><artnum>35</artnum><issn>1476-7120</issn><eissn>1476-7120</eissn><abstract>Despite advances in medical therapy, cardiovascular disease, mainly coronary artery disease (CAD), remains the leading cause of mortality among patients with diabetes mellitus (DM). The objective of the present study was to assess the effectiveness of dipyridamole stress echocardiography in identify diabetic patients at high risk for cardiovascular events. Dipyridamole stress echocardiography was administered to 483 diabetic patients (294 women; mean age 63.41 ± 11.28 years) between July 2006 and December 2012. Follow-up data were available for 264 patients (163 women; mean age 64.3 ± 10.5 years): 250 with a negative stress echocardiography and 14 with a positive stress echo. During a mean follow-up time of 18 ± 14 months, a cardiovascular event occurred in 18 (6.8%) patients, 12 (4.8%) in patients with a negative stress echo (n = 250) during a mean follow-up period of 20 ± 16 months and 6 (42%) in patients with positive stress echo (n = 14) during a mean follow-up of 13 ± 13 months. The positive and negative predictive values of stress echocardiography were 42% and 96% respectively. The accuracy value was 92%. A Cox regression model showed that CAD (hazard ratio [HR] 5.4, 95% confidence interval [CI] 1.9-15.4; p = 0.002) and positive stress echocardiography (HR 7.1, 95% CI 2.5-20.5; p &lt; 0.001) were significant predictors of cardiovascular events. For patients with diabetes, a negative dipyridamole stress echocardiogram predicts favorable outcome during the first year of follow-up. A new stress imaging test should be done after 12 months in diabetic patients.</abstract><cop>England</cop><pub>BioMed Central</pub><pmid>26209102</pmid><doi>10.1186/s12947-015-0030-7</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1476-7120
ispartof Cardiovascular ultrasound, 2015-07, Vol.13 (1), p.35-35, Article 35
issn 1476-7120
1476-7120
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4515011
source Publicly Available Content Database; PubMed Central
subjects Brazil - epidemiology
Comorbidity
Coronary Artery Disease - diagnostic imaging
Coronary Artery Disease - mortality
Diabetes Complications - diagnostic imaging
Diabetes Complications - mortality
Dipyridamole
Echocardiography, Stress - statistics & numerical data
Exercise Test
Female
Humans
Incidence
Male
Middle Aged
Prognosis
Reproducibility of Results
Risk Assessment - methods
Sensitivity and Specificity
Survival Analysis
Vasodilator Agents
title Assessment of dipyridamole stress echocardiography for risk stratification of diabetic patients
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T13%3A15%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Assessment%20of%20dipyridamole%20stress%20echocardiography%20for%20risk%20stratification%20of%20diabetic%20patients&rft.jtitle=Cardiovascular%20ultrasound&rft.au=Baroncini,%20Liz%20Andr%C3%A9a%20Villela&rft.date=2015-07-25&rft.volume=13&rft.issue=1&rft.spage=35&rft.epage=35&rft.pages=35-35&rft.artnum=35&rft.issn=1476-7120&rft.eissn=1476-7120&rft_id=info:doi/10.1186/s12947-015-0030-7&rft_dat=%3Cproquest_pubme%3E1699491356%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c466t-8957039c86407daafda79e163659e5efd4c8c2ca871f778887eef1cc40125ac63%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1699491356&rft_id=info:pmid/26209102&rfr_iscdi=true