Factors Associated With Long-Term Weight Loss Following Bariatric Surgery Using 2 Methods for Repeated Measures Analysis

We used electronic health record data from 162 patients enrolled in the NUgene Project (2002-2013) to determine demographic factors associated with long-term (from 1 to up to 9.5 (mean = 5.6) years) weight loss following Roux-en-Y gastric bypass surgery. Ninety-nine (61.1%) patients self-reported wh...

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Bibliographic Details
Published in:American journal of epidemiology 2015-08, Vol.182 (3), p.235-243
Main Authors: Baldridge, Abigail S, Pacheco, Jennifer A, Aufox, Sharon A, Kim, Kwang-Youn A, Silverstein, J C, Denham, W, Hungness, E, Smith, Maureen E, Allen, Norrina B, Greenland, Philip, Rasmussen-Torvik, Laura J
Format: Article
Language:English
Subjects:
Analysis of Variance
Demographics
Electronic health records
Ethnicity
Female
Follow-Up Studies
Gastric Bypass - statistics & numerical data
Heart surgery
Humans
Linear Models
Male
Middle Aged
Obesity, Morbid - surgery
Practice of Epidemiology
Self Report
Time
Treatment Outcome
Weight control
Weight Loss - ethnology
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Summary:We used electronic health record data from 162 patients enrolled in the NUgene Project (2002-2013) to determine demographic factors associated with long-term (from 1 to up to 9.5 (mean = 5.6) years) weight loss following Roux-en-Y gastric bypass surgery. Ninety-nine (61.1%) patients self-reported white, and 63 (38.9%) self-reported black, mixed, or missing race. The average percent weight loss was -33.4% (standard deviation, 9.3) at 1 year after surgery and -30.7% (standard deviation, 12.5) at the last follow-up point. We used linear mixed and semiparametric trajectory models to test the association of surgical and demographic factors (height, surgery age, surgery weight, surgery body mass index, marital status, sex, educational level, site, International Classification of Diseases code, Current Procedural Terminology code, Hispanic ethnicity, and self-reported race) with long-term percent weight loss and pattern of weight loss. We found that black, mixed, and missing races (combined) in comparison with white race were associated with a decreased percent weight loss of -4.31% (95% confidence interval: -7.30, -1.32) and were less likely to have higher and sustained percent weight loss (P = 0.04). We also found that less obese patients were less likely to have higher and sustained percent weight loss (P = 0.01). These findings may be helpful to patients in setting expectations after weight loss surgery.
ISSN:0002-9262
1476-6256
DOI:10.1093/aje/kwv039