Loading…

PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels

We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN. The server provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mou...

Full description

Saved in:
Bibliographic Details
Published in:Bioinformatics 2015-08, Vol.31 (16), p.2745-2747
Main Authors: Choi, Yongwook, Chan, Agnes P
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c543t-b41f697802b3cad3878ba94b0c889d89869aaee5efc071f800a04541f7e30f3c3
cites cdi_FETCH-LOGICAL-c543t-b41f697802b3cad3878ba94b0c889d89869aaee5efc071f800a04541f7e30f3c3
container_end_page 2747
container_issue 16
container_start_page 2745
container_title Bioinformatics
container_volume 31
creator Choi, Yongwook
Chan, Agnes P
description We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN. The server provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mouse variants at both the genomic and protein levels. The web server is freely available and open to all users with no login requirements at http://provean.jcvi.org. achan@jcvi.org Supplementary data are available at Bioinformatics online.
doi_str_mv 10.1093/bioinformatics/btv195
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4528627</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1709172610</sourcerecordid><originalsourceid>FETCH-LOGICAL-c543t-b41f697802b3cad3878ba94b0c889d89869aaee5efc071f800a04541f7e30f3c3</originalsourceid><addsrcrecordid>eNqNUU1PHDEMjaqi8tWf0CrHXhaSyWSS9FAJIb4kBAjRXqMk45RUM8k2yWzFv2dWC6ty42Jb9ntPth9CXyg5okSxYxtSiD7l0dTgyrGtK6r4B7RHWScWraT047YmbBftl_KHEMIJ7z6h3YZLTlWr9pC9u7_9dXZyg_-BxQXyCvJ3bHBNaZgDXmbog6u4PgL2U3Q1pGgGDN7D3E0emzHEhI0LPS6TLTXUaY0p2MQeh9jDUA7RjjdDgc8v-QD9PD97OL1cXN9eXJ2eXC8cb1ld2Jb6TglJGsuc6ZkU0hrVWuKkVL1UslPGAHDwjgjqJSGGtHwmCWDEM8cO0I-N7nKyI_QOYs1m0MscRpOfdDJBv53E8Kh_p5VueSO7RswC314Ecvo7Qal6DMXBMJgIaSqaCjZ_sBOUvwNKFBVNR8l7oE3HOWNrVb6BupxKyeC3y1Oi167rt67rjesz7-v_l29ZrzazZ4lLrzg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1702655335</pqid></control><display><type>article</type><title>PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels</title><source>PubMed Central</source><source>Oxford Open Access Journals</source><creator>Choi, Yongwook ; Chan, Agnes P</creator><creatorcontrib>Choi, Yongwook ; Chan, Agnes P</creatorcontrib><description>We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN. The server provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mouse variants at both the genomic and protein levels. The web server is freely available and open to all users with no login requirements at http://provean.jcvi.org. achan@jcvi.org Supplementary data are available at Bioinformatics online.</description><identifier>ISSN: 1367-4803</identifier><identifier>EISSN: 1367-4811</identifier><identifier>EISSN: 1460-2059</identifier><identifier>DOI: 10.1093/bioinformatics/btv195</identifier><identifier>PMID: 25851949</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Access control to computer data ; Amino Acid Substitution - genetics ; Amino acids ; Animals ; Applications Notes ; Bioinformatics ; Deletion ; Genetic Variation ; Genome ; Humans ; INDEL Mutation - genetics ; Internet ; Mice ; Proteins ; Proteins - chemistry ; Proteins - genetics ; Sequence Deletion ; Servers (computers) ; Software ; World Wide Web</subject><ispartof>Bioinformatics, 2015-08, Vol.31 (16), p.2745-2747</ispartof><rights>The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.</rights><rights>The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c543t-b41f697802b3cad3878ba94b0c889d89869aaee5efc071f800a04541f7e30f3c3</citedby><cites>FETCH-LOGICAL-c543t-b41f697802b3cad3878ba94b0c889d89869aaee5efc071f800a04541f7e30f3c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528627/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528627/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,724,777,781,882,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25851949$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Choi, Yongwook</creatorcontrib><creatorcontrib>Chan, Agnes P</creatorcontrib><title>PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels</title><title>Bioinformatics</title><addtitle>Bioinformatics</addtitle><description>We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN. The server provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mouse variants at both the genomic and protein levels. The web server is freely available and open to all users with no login requirements at http://provean.jcvi.org. achan@jcvi.org Supplementary data are available at Bioinformatics online.</description><subject>Access control to computer data</subject><subject>Amino Acid Substitution - genetics</subject><subject>Amino acids</subject><subject>Animals</subject><subject>Applications Notes</subject><subject>Bioinformatics</subject><subject>Deletion</subject><subject>Genetic Variation</subject><subject>Genome</subject><subject>Humans</subject><subject>INDEL Mutation - genetics</subject><subject>Internet</subject><subject>Mice</subject><subject>Proteins</subject><subject>Proteins - chemistry</subject><subject>Proteins - genetics</subject><subject>Sequence Deletion</subject><subject>Servers (computers)</subject><subject>Software</subject><subject>World Wide Web</subject><issn>1367-4803</issn><issn>1367-4811</issn><issn>1460-2059</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNqNUU1PHDEMjaqi8tWf0CrHXhaSyWSS9FAJIb4kBAjRXqMk45RUM8k2yWzFv2dWC6ty42Jb9ntPth9CXyg5okSxYxtSiD7l0dTgyrGtK6r4B7RHWScWraT047YmbBftl_KHEMIJ7z6h3YZLTlWr9pC9u7_9dXZyg_-BxQXyCvJ3bHBNaZgDXmbog6u4PgL2U3Q1pGgGDN7D3E0emzHEhI0LPS6TLTXUaY0p2MQeh9jDUA7RjjdDgc8v-QD9PD97OL1cXN9eXJ2eXC8cb1ld2Jb6TglJGsuc6ZkU0hrVWuKkVL1UslPGAHDwjgjqJSGGtHwmCWDEM8cO0I-N7nKyI_QOYs1m0MscRpOfdDJBv53E8Kh_p5VueSO7RswC314Ecvo7Qal6DMXBMJgIaSqaCjZ_sBOUvwNKFBVNR8l7oE3HOWNrVb6BupxKyeC3y1Oi167rt67rjesz7-v_l29ZrzazZ4lLrzg</recordid><startdate>20150815</startdate><enddate>20150815</enddate><creator>Choi, Yongwook</creator><creator>Chan, Agnes P</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7QO</scope><scope>7TM</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7SC</scope><scope>JQ2</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>5PM</scope></search><sort><creationdate>20150815</creationdate><title>PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels</title><author>Choi, Yongwook ; Chan, Agnes P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c543t-b41f697802b3cad3878ba94b0c889d89869aaee5efc071f800a04541f7e30f3c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Access control to computer data</topic><topic>Amino Acid Substitution - genetics</topic><topic>Amino acids</topic><topic>Animals</topic><topic>Applications Notes</topic><topic>Bioinformatics</topic><topic>Deletion</topic><topic>Genetic Variation</topic><topic>Genome</topic><topic>Humans</topic><topic>INDEL Mutation - genetics</topic><topic>Internet</topic><topic>Mice</topic><topic>Proteins</topic><topic>Proteins - chemistry</topic><topic>Proteins - genetics</topic><topic>Sequence Deletion</topic><topic>Servers (computers)</topic><topic>Software</topic><topic>World Wide Web</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Choi, Yongwook</creatorcontrib><creatorcontrib>Chan, Agnes P</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Biotechnology Research Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>ProQuest Computer Science Collection</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts – Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Bioinformatics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Choi, Yongwook</au><au>Chan, Agnes P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels</atitle><jtitle>Bioinformatics</jtitle><addtitle>Bioinformatics</addtitle><date>2015-08-15</date><risdate>2015</risdate><volume>31</volume><issue>16</issue><spage>2745</spage><epage>2747</epage><pages>2745-2747</pages><issn>1367-4803</issn><eissn>1367-4811</eissn><eissn>1460-2059</eissn><abstract>We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN. The server provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mouse variants at both the genomic and protein levels. The web server is freely available and open to all users with no login requirements at http://provean.jcvi.org. achan@jcvi.org Supplementary data are available at Bioinformatics online.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>25851949</pmid><doi>10.1093/bioinformatics/btv195</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1367-4803
ispartof Bioinformatics, 2015-08, Vol.31 (16), p.2745-2747
issn 1367-4803
1367-4811
1460-2059
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4528627
source PubMed Central; Oxford Open Access Journals
subjects Access control to computer data
Amino Acid Substitution - genetics
Amino acids
Animals
Applications Notes
Bioinformatics
Deletion
Genetic Variation
Genome
Humans
INDEL Mutation - genetics
Internet
Mice
Proteins
Proteins - chemistry
Proteins - genetics
Sequence Deletion
Servers (computers)
Software
World Wide Web
title PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T20%3A56%3A29IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=PROVEAN%20web%20server:%20a%20tool%20to%20predict%20the%20functional%20effect%20of%20amino%20acid%20substitutions%20and%20indels&rft.jtitle=Bioinformatics&rft.au=Choi,%20Yongwook&rft.date=2015-08-15&rft.volume=31&rft.issue=16&rft.spage=2745&rft.epage=2747&rft.pages=2745-2747&rft.issn=1367-4803&rft.eissn=1367-4811&rft_id=info:doi/10.1093/bioinformatics/btv195&rft_dat=%3Cproquest_pubme%3E1709172610%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c543t-b41f697802b3cad3878ba94b0c889d89869aaee5efc071f800a04541f7e30f3c3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1702655335&rft_id=info:pmid/25851949&rfr_iscdi=true