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PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels
We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN. The server provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mou...
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Published in: | Bioinformatics 2015-08, Vol.31 (16), p.2745-2747 |
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container_issue | 16 |
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container_title | Bioinformatics |
container_volume | 31 |
creator | Choi, Yongwook Chan, Agnes P |
description | We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN. The server provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mouse variants at both the genomic and protein levels.
The web server is freely available and open to all users with no login requirements at http://provean.jcvi.org.
achan@jcvi.org
Supplementary data are available at Bioinformatics online. |
doi_str_mv | 10.1093/bioinformatics/btv195 |
format | article |
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The web server is freely available and open to all users with no login requirements at http://provean.jcvi.org.
achan@jcvi.org
Supplementary data are available at Bioinformatics online.</description><identifier>ISSN: 1367-4803</identifier><identifier>EISSN: 1367-4811</identifier><identifier>EISSN: 1460-2059</identifier><identifier>DOI: 10.1093/bioinformatics/btv195</identifier><identifier>PMID: 25851949</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Access control to computer data ; Amino Acid Substitution - genetics ; Amino acids ; Animals ; Applications Notes ; Bioinformatics ; Deletion ; Genetic Variation ; Genome ; Humans ; INDEL Mutation - genetics ; Internet ; Mice ; Proteins ; Proteins - chemistry ; Proteins - genetics ; Sequence Deletion ; Servers (computers) ; Software ; World Wide Web</subject><ispartof>Bioinformatics, 2015-08, Vol.31 (16), p.2745-2747</ispartof><rights>The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.</rights><rights>The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c543t-b41f697802b3cad3878ba94b0c889d89869aaee5efc071f800a04541f7e30f3c3</citedby><cites>FETCH-LOGICAL-c543t-b41f697802b3cad3878ba94b0c889d89869aaee5efc071f800a04541f7e30f3c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528627/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528627/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,724,777,781,882,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25851949$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Choi, Yongwook</creatorcontrib><creatorcontrib>Chan, Agnes P</creatorcontrib><title>PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels</title><title>Bioinformatics</title><addtitle>Bioinformatics</addtitle><description>We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN. The server provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mouse variants at both the genomic and protein levels.
The web server is freely available and open to all users with no login requirements at http://provean.jcvi.org.
achan@jcvi.org
Supplementary data are available at Bioinformatics online.</description><subject>Access control to computer data</subject><subject>Amino Acid Substitution - genetics</subject><subject>Amino acids</subject><subject>Animals</subject><subject>Applications Notes</subject><subject>Bioinformatics</subject><subject>Deletion</subject><subject>Genetic Variation</subject><subject>Genome</subject><subject>Humans</subject><subject>INDEL Mutation - genetics</subject><subject>Internet</subject><subject>Mice</subject><subject>Proteins</subject><subject>Proteins - chemistry</subject><subject>Proteins - genetics</subject><subject>Sequence Deletion</subject><subject>Servers (computers)</subject><subject>Software</subject><subject>World Wide Web</subject><issn>1367-4803</issn><issn>1367-4811</issn><issn>1460-2059</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNqNUU1PHDEMjaqi8tWf0CrHXhaSyWSS9FAJIb4kBAjRXqMk45RUM8k2yWzFv2dWC6ty42Jb9ntPth9CXyg5okSxYxtSiD7l0dTgyrGtK6r4B7RHWScWraT047YmbBftl_KHEMIJ7z6h3YZLTlWr9pC9u7_9dXZyg_-BxQXyCvJ3bHBNaZgDXmbog6u4PgL2U3Q1pGgGDN7D3E0emzHEhI0LPS6TLTXUaY0p2MQeh9jDUA7RjjdDgc8v-QD9PD97OL1cXN9eXJ2eXC8cb1ld2Jb6TglJGsuc6ZkU0hrVWuKkVL1UslPGAHDwjgjqJSGGtHwmCWDEM8cO0I-N7nKyI_QOYs1m0MscRpOfdDJBv53E8Kh_p5VueSO7RswC314Ecvo7Qal6DMXBMJgIaSqaCjZ_sBOUvwNKFBVNR8l7oE3HOWNrVb6BupxKyeC3y1Oi167rt67rjesz7-v_l29ZrzazZ4lLrzg</recordid><startdate>20150815</startdate><enddate>20150815</enddate><creator>Choi, Yongwook</creator><creator>Chan, Agnes P</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7QO</scope><scope>7TM</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7SC</scope><scope>JQ2</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>5PM</scope></search><sort><creationdate>20150815</creationdate><title>PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels</title><author>Choi, Yongwook ; Chan, Agnes P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c543t-b41f697802b3cad3878ba94b0c889d89869aaee5efc071f800a04541f7e30f3c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Access control to computer data</topic><topic>Amino Acid Substitution - genetics</topic><topic>Amino acids</topic><topic>Animals</topic><topic>Applications Notes</topic><topic>Bioinformatics</topic><topic>Deletion</topic><topic>Genetic Variation</topic><topic>Genome</topic><topic>Humans</topic><topic>INDEL Mutation - genetics</topic><topic>Internet</topic><topic>Mice</topic><topic>Proteins</topic><topic>Proteins - chemistry</topic><topic>Proteins - genetics</topic><topic>Sequence Deletion</topic><topic>Servers (computers)</topic><topic>Software</topic><topic>World Wide Web</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Choi, Yongwook</creatorcontrib><creatorcontrib>Chan, Agnes P</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Biotechnology Research Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>ProQuest Computer Science Collection</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts – Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Bioinformatics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Choi, Yongwook</au><au>Chan, Agnes P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels</atitle><jtitle>Bioinformatics</jtitle><addtitle>Bioinformatics</addtitle><date>2015-08-15</date><risdate>2015</risdate><volume>31</volume><issue>16</issue><spage>2745</spage><epage>2747</epage><pages>2745-2747</pages><issn>1367-4803</issn><eissn>1367-4811</eissn><eissn>1460-2059</eissn><abstract>We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN. The server provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mouse variants at both the genomic and protein levels.
The web server is freely available and open to all users with no login requirements at http://provean.jcvi.org.
achan@jcvi.org
Supplementary data are available at Bioinformatics online.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>25851949</pmid><doi>10.1093/bioinformatics/btv195</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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language | eng |
recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4528627 |
source | PubMed Central; Oxford Open Access Journals |
subjects | Access control to computer data Amino Acid Substitution - genetics Amino acids Animals Applications Notes Bioinformatics Deletion Genetic Variation Genome Humans INDEL Mutation - genetics Internet Mice Proteins Proteins - chemistry Proteins - genetics Sequence Deletion Servers (computers) Software World Wide Web |
title | PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels |
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