Twenty-four hour urinary C-peptide and fasting plasma C-peptide as indicators of metabolic control in 83 insulin dependent diabetic patients

In order to evaluate the usefulness of 24-hour urinary C-peptide and fasting plasma C-peptide as metabolic index, C-peptide was measured in 24-hour urine and in fasting plasma of 83 insulin dependent diabetic patients. Using multiple linear regression, HbAlc was analyzed as a dependent variable vers...

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Bibliographic Details
Published in:The Korean journal of internal medicine 1987-07, Vol.2 (2), p.196-201
Main Authors: Yoo, H J, Hartling, S G, Binder, C
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
C-Peptide - blood
C-Peptide - urine
Child
Diabetes Mellitus, Type 1 - drug therapy
Diabetes Mellitus, Type 1 - metabolism
Fasting
Female
Glycated Hemoglobin - metabolism
Humans
Insulin - administration & dosage
Male
Middle Aged
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Summary:In order to evaluate the usefulness of 24-hour urinary C-peptide and fasting plasma C-peptide as metabolic index, C-peptide was measured in 24-hour urine and in fasting plasma of 83 insulin dependent diabetic patients. Using multiple linear regression, HbAlc was analyzed as a dependent variable versus independent variables such as daily insulin dose, fasting plasma C-peptide and 24-hour urinary C-peptide. Twentyfour hour urinary C-peptide was significantly correlated with fasting plasma C-peptide showed significant inverse correlations with the daily insulin dose. But neither 24-hour urinary C-peptide nor fasting plasma C-peptide was significantly correlated with HbAlc as a dependent variable. These results show that there was no difference of usefulness between 24-hour urinary C-peptide and fasting plasma C-peptide in relation to HbAlc and daily insulin dose in insulin dependent diabetic patients.
ISSN:1226-3303
2005-6648
DOI:10.3904/kjim.1987.2.2.196