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A pelvic mass on ultrasonography and high human chorionic gonadotropin level: not always an ectopic pregnancy
A 24-year-old patient with 7-week amenorrhoea consulted for vaginal bleeding without abdominal pain. Ultrasonography revealed a 7 × 4 cm solid right pelvic mass. There was no visible intrauterine gestational sac. The serum β-human chorionic gonadotropin (β-hCG) level was 11 998 IU/l. Emergency lapar...
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Published in: | BMJ case reports 2012-06, Vol.2012 (may30 1), p.bcr0120125577-bcr0120125577 |
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description | A 24-year-old patient with 7-week amenorrhoea consulted for vaginal bleeding without abdominal pain. Ultrasonography revealed a 7 × 4 cm solid right pelvic mass. There was no visible intrauterine gestational sac. The serum β-human chorionic gonadotropin (β-hCG) level was 11 998 IU/l. Emergency laparoscopy was performed for a presumptive diagnosis of ectopic pregnancy. At laparoscopy, the right ovary was enlarged with a non-haemorrhagic 7 × 4 cm solid lesion, which was resected. The histological diagnosis was a dysgerminoma with immunohistochemistry showing nests of syncytiotrophoblastic cells, which were the origin of the hCG production. There was no pregnancy, either intrauterine or ectopic. There was no evidence of metastasis from the dysgerminoma on the positron-emission tomography scanner. The patient underwent a second procedure for surgical staging of this ovarian germ-cell tumour. This ovarian dysgerminoma was staged FIGO 1A, and the patient did not receive adjuvant therapy. There was no recurrence at the last 8-month follow-up. |
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Ultrasonography revealed a 7 × 4 cm solid right pelvic mass. There was no visible intrauterine gestational sac. The serum β-human chorionic gonadotropin (β-hCG) level was 11 998 IU/l. Emergency laparoscopy was performed for a presumptive diagnosis of ectopic pregnancy. At laparoscopy, the right ovary was enlarged with a non-haemorrhagic 7 × 4 cm solid lesion, which was resected. The histological diagnosis was a dysgerminoma with immunohistochemistry showing nests of syncytiotrophoblastic cells, which were the origin of the hCG production. There was no pregnancy, either intrauterine or ectopic. There was no evidence of metastasis from the dysgerminoma on the positron-emission tomography scanner. The patient underwent a second procedure for surgical staging of this ovarian germ-cell tumour. This ovarian dysgerminoma was staged FIGO 1A, and the patient did not receive adjuvant therapy. 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Ultrasonography revealed a 7 × 4 cm solid right pelvic mass. There was no visible intrauterine gestational sac. The serum β-human chorionic gonadotropin (β-hCG) level was 11 998 IU/l. Emergency laparoscopy was performed for a presumptive diagnosis of ectopic pregnancy. At laparoscopy, the right ovary was enlarged with a non-haemorrhagic 7 × 4 cm solid lesion, which was resected. The histological diagnosis was a dysgerminoma with immunohistochemistry showing nests of syncytiotrophoblastic cells, which were the origin of the hCG production. There was no pregnancy, either intrauterine or ectopic. There was no evidence of metastasis from the dysgerminoma on the positron-emission tomography scanner. The patient underwent a second procedure for surgical staging of this ovarian germ-cell tumour. This ovarian dysgerminoma was staged FIGO 1A, and the patient did not receive adjuvant therapy. There was no recurrence at the last 8-month follow-up.</description><subject>Black</subject><subject>Chorionic Gonadotropin, beta Subunit, Human - blood</subject><subject>Cysts</subject><subject>Diagnosis, Differential</subject><subject>Dysgerminoma - blood</subject><subject>Dysgerminoma - diagnostic imaging</subject><subject>Dysgerminoma - surgery</subject><subject>Europe (West)</subject><subject>Female</subject><subject>Humans</subject><subject>Laparoscopy</subject><subject>Laparoscopy - methods</subject><subject>Learning from Errors</subject><subject>Ovarian Neoplasms - blood</subject><subject>Ovarian Neoplasms - diagnostic imaging</subject><subject>Ovarian Neoplasms - surgery</subject><subject>Ovaries</subject><subject>Pelvis - diagnostic imaging</subject><subject>Phosphatase</subject><subject>Pregnancy</subject><subject>Pregnancy complications</subject><subject>Pregnancy, Ectopic - diagnosis</subject><subject>Tumors</subject><subject>Ultrasonic imaging</subject><subject>Ultrasonography, Prenatal - methods</subject><subject>Uterus</subject><subject>Young Adult</subject><issn>1757-790X</issn><issn>1757-790X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNqFkc1r3DAQxUVpSEKae09F0Euh7FZftlY9FEJI2kIglxZ6E2N5_LHYkivZG_a_r5ZNQtpLdRnB_N5jHo-Qt5ytOZflp8rFNeNrwbhYF4XWr8g514VeacN-vX7xPyOXKW1ZfpKrjZKn5EyIsjSGm3MyXtEJh13v6Agp0eDpMswRUvChjTB1ewq-pl3fdrRbRvDUdSH2wWdBGzzUYY5h6j0dcIfDZ-rDTGF4gH3KOopuzktHp4itB-_2b8hJA0PCy8d5QX7e3vy4_ra6u__6_frqblUpla9WBlGpCou6bsBURSNkI10pS44Sna64qGuj0ShuSqgdoNZSgNgUGpCVuJEX5MvRd1qqEWuHPmca7BT7EeLeBujt3xvfd7YNO6sKJQWT2eDDo0EMvxdMsx375HAYwGNYkuWMG2YEK3hG3_-DbsMSfY5nud5IoZVRLFPsSLkYUorYPB_DmT3UaXOdlnF7qNMe6sySdy9DPAueysvAxyNQjdv_2_0BJKurew</recordid><startdate>20120601</startdate><enddate>20120601</enddate><creator>Rozenholc, Alexandre</creator><creator>Abdulcadir, Jasmine</creator><creator>Pelte, Marie-Françoise</creator><creator>Petignat, Patrick</creator><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20120601</creationdate><title>A pelvic mass on ultrasonography and high human chorionic gonadotropin level: not always an ectopic pregnancy</title><author>Rozenholc, Alexandre ; Abdulcadir, Jasmine ; Pelte, Marie-Françoise ; Petignat, Patrick</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b4457-49ee44be5ddfa9b5f23f3c6361e3ec7b12dd97e94196adcae7732a2857ae06e83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Black</topic><topic>Chorionic Gonadotropin, beta Subunit, Human - blood</topic><topic>Cysts</topic><topic>Diagnosis, Differential</topic><topic>Dysgerminoma - blood</topic><topic>Dysgerminoma - diagnostic imaging</topic><topic>Dysgerminoma - surgery</topic><topic>Europe (West)</topic><topic>Female</topic><topic>Humans</topic><topic>Laparoscopy</topic><topic>Laparoscopy - methods</topic><topic>Learning from Errors</topic><topic>Ovarian Neoplasms - blood</topic><topic>Ovarian Neoplasms - diagnostic imaging</topic><topic>Ovarian Neoplasms - surgery</topic><topic>Ovaries</topic><topic>Pelvis - diagnostic imaging</topic><topic>Phosphatase</topic><topic>Pregnancy</topic><topic>Pregnancy complications</topic><topic>Pregnancy, Ectopic - diagnosis</topic><topic>Tumors</topic><topic>Ultrasonic imaging</topic><topic>Ultrasonography, Prenatal - methods</topic><topic>Uterus</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rozenholc, Alexandre</creatorcontrib><creatorcontrib>Abdulcadir, Jasmine</creatorcontrib><creatorcontrib>Pelte, Marie-Françoise</creatorcontrib><creatorcontrib>Petignat, Patrick</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Nursing and Allied Health Journals</collection><collection>ProQuest_Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMJ case reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rozenholc, Alexandre</au><au>Abdulcadir, Jasmine</au><au>Pelte, Marie-Françoise</au><au>Petignat, Patrick</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A pelvic mass on ultrasonography and high human chorionic gonadotropin level: not always an ectopic pregnancy</atitle><jtitle>BMJ case reports</jtitle><addtitle>BMJ Case Rep</addtitle><date>2012-06-01</date><risdate>2012</risdate><volume>2012</volume><issue>may30 1</issue><spage>bcr0120125577</spage><epage>bcr0120125577</epage><pages>bcr0120125577-bcr0120125577</pages><issn>1757-790X</issn><eissn>1757-790X</eissn><abstract>A 24-year-old patient with 7-week amenorrhoea consulted for vaginal bleeding without abdominal pain. Ultrasonography revealed a 7 × 4 cm solid right pelvic mass. There was no visible intrauterine gestational sac. The serum β-human chorionic gonadotropin (β-hCG) level was 11 998 IU/l. Emergency laparoscopy was performed for a presumptive diagnosis of ectopic pregnancy. At laparoscopy, the right ovary was enlarged with a non-haemorrhagic 7 × 4 cm solid lesion, which was resected. The histological diagnosis was a dysgerminoma with immunohistochemistry showing nests of syncytiotrophoblastic cells, which were the origin of the hCG production. There was no pregnancy, either intrauterine or ectopic. There was no evidence of metastasis from the dysgerminoma on the positron-emission tomography scanner. The patient underwent a second procedure for surgical staging of this ovarian germ-cell tumour. This ovarian dysgerminoma was staged FIGO 1A, and the patient did not receive adjuvant therapy. There was no recurrence at the last 8-month follow-up.</abstract><cop>England</cop><pub>BMJ Publishing Group LTD</pub><pmid>22669919</pmid><doi>10.1136/bcr.01.2012.5577</doi><oa>free_for_read</oa></addata></record> |
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subjects | Black Chorionic Gonadotropin, beta Subunit, Human - blood Cysts Diagnosis, Differential Dysgerminoma - blood Dysgerminoma - diagnostic imaging Dysgerminoma - surgery Europe (West) Female Humans Laparoscopy Laparoscopy - methods Learning from Errors Ovarian Neoplasms - blood Ovarian Neoplasms - diagnostic imaging Ovarian Neoplasms - surgery Ovaries Pelvis - diagnostic imaging Phosphatase Pregnancy Pregnancy complications Pregnancy, Ectopic - diagnosis Tumors Ultrasonic imaging Ultrasonography, Prenatal - methods Uterus Young Adult |
title | A pelvic mass on ultrasonography and high human chorionic gonadotropin level: not always an ectopic pregnancy |
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