Olfactory identification deficits and increased mortality in the community

Objective To examine the association between odor identification deficits and future mortality in a multiethnic community cohort of older adults. Methods Participants were evaluated with the 40‐item University of Pennsylvania Smell Identification Test (UPSIT). Follow‐up occurred at 2‐year intervals...

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Bibliographic Details
Published in:Annals of neurology 2015-09, Vol.78 (3), p.401-411
Main Authors: Devanand, Davangere P., Lee, Seonjoo, Manly, Jennifer, Andrews, Howard, Schupf, Nicole, Masurkar, Arjun, Stern, Yaakov, Mayeux, Richard, Doty, Richard L.
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Cohort Studies
Comorbidity
Confidence intervals
Dementia
Female
Follow-Up Studies
Humans
Male
Mortality
Mortality - trends
Older people
Olfaction Disorders - diagnosis
Olfaction Disorders - mortality
Residence Characteristics
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Summary:Objective To examine the association between odor identification deficits and future mortality in a multiethnic community cohort of older adults. Methods Participants were evaluated with the 40‐item University of Pennsylvania Smell Identification Test (UPSIT). Follow‐up occurred at 2‐year intervals with information on death obtained from informant interviews and the National Death Index. Results During follow‐up (mean = 4.1 years, standard deviation = 2.6), 349 of 1,169 (29.9%) participants died. Participants who died were more likely to be older (p 
ISSN:0364-5134
1531-8249
DOI:10.1002/ana.24447