Metabolic Syndrome Components are Associated with Increased Prostate Cancer Risk

Our study investigated the associations of metabolic syndrome (MS) and metabolic indicators with prostate cancer (PCa) risk in the Chinese Han ethnic population. We studied 101 PCa patients (without/with MS) and 120 healthy controls. Clinical data, including waist circumference, BMI, TG, FINS, FBG,...

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Bibliographic Details
Published in:Medical science monitor 2015-08, Vol.21, p.2387-2396
Main Authors: Zhang, Jian-Qin, Geng, Hui, Ma, Mao, Nan, Xun-Yi, Sheng, Bin-Wu
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Asian Continental Ancestry Group
Blood Glucose - metabolism
Body Mass Index
Case-Control Studies
China
Cholesterol, HDL - blood
Cholesterol, LDL - blood
Clinical Research
Humans
Insulin Resistance
Kallikreins - blood
Logistic Models
Male
Metabolic Syndrome - blood
Metabolic Syndrome - complications
Metabolic Syndrome - pathology
Middle Aged
Neoplasm Grading
Organ Size
Prostate-Specific Antigen - blood
Prostatic Neoplasms - blood
Prostatic Neoplasms - etiology
Prostatic Neoplasms - pathology
Risk Factors
Triglycerides - blood
Waist Circumference
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Summary:Our study investigated the associations of metabolic syndrome (MS) and metabolic indicators with prostate cancer (PCa) risk in the Chinese Han ethnic population. We studied 101 PCa patients (without/with MS) and 120 healthy controls. Clinical data, including waist circumference, BMI, TG, FINS, FBG, and PCa-related indicators, were collected. The correlations between MS and PCa were analyzed. Compared to PCa, PV and Gleason scores increased and PSA levels decreased in PCa with MS group (all P
ISSN:1643-3750
1234-1010
1643-3750
DOI:10.12659/MSM.893442