Motor System Reorganization After Stroke: Stimulating and Training Toward Perfection

Stroke instigates regenerative responses that reorganize connectivity patterns among surviving neurons. The new connectivity patterns can be suboptimal for behavioral function. This review summarizes current knowledge on post-stroke motor system reorganization and emerging strategies for shaping it...

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Bibliographic Details
Published in:Physiology (Bethesda, Md.) Md.), 2015-09, Vol.30 (5), p.358-370
Main Authors: Jones, Theresa A, Adkins, DeAnna L
Format: Article
Language:English
Subjects:
Animals
Combined Modality Therapy
Electric Stimulation Therapy - methods
Exercise Movement Techniques - methods
Humans
Motor Activity
Motor Cortex - physiopathology
Neural Pathways - physiopathology
Neuronal Plasticity
Recovery of Function
Restraint, Physical
Reviews
Stroke - physiopathology
Stroke - psychology
Stroke Rehabilitation
Treatment Outcome
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Summary:Stroke instigates regenerative responses that reorganize connectivity patterns among surviving neurons. The new connectivity patterns can be suboptimal for behavioral function. This review summarizes current knowledge on post-stroke motor system reorganization and emerging strategies for shaping it with manipulations of behavior and cortical activity to improve functional outcome.
ISSN:1548-9213
1548-9221
DOI:10.1152/physiol.00014.2015