Evaluation of Antileishmanial Activity of Albaha Medicinal Plants against Leishmania amazonensis

Sixteen methanolic extracts obtained from thirteen plant species, selected either from ethnobotanical or chemotaxonomical data, were screened for their antileishmanial activity against Leishmania amazonensis. The cytotoxic activity against normal peritoneal macrophages from normal BALB/c mice was al...

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Bibliographic Details
Published in:BioMed research international 2015-01, Vol.2015 (2015), p.1-6
Main Authors: Al-Fatimi, Mohamed A., Monzote, Lianet, Ali, Nasser A. Awadh, Al-Sokari, Saeed S.
Format: Article
Language:English
Subjects:
Achillea
Animals
Antibiotics
Antiprotozoal Agents - pharmacology
Care and treatment
Cytotoxicity
Euphorbia helioscopia
Flowers & plants
Health aspects
Herbal medicine
Kinases
Leishmania amazonensis
Leishmania mexicana - drug effects
Leishmaniasis
Macrophages, Peritoneal - drug effects
Medicinal plants
Medicine, Botanic
Medicine, Herbal
Mice
Mice, Inbred BALB C
Parasites
Parasitic diseases
Pharmacy
Plant Extracts - pharmacology
Plant Leaves - chemistry
Plants, Medicinal - chemistry
Solanum incanum
Studies
Tropical diseases
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Summary:Sixteen methanolic extracts obtained from thirteen plant species, selected either from ethnobotanical or chemotaxonomical data, were screened for their antileishmanial activity against Leishmania amazonensis. The cytotoxic activity against normal peritoneal macrophages from normal BALB/c mice was also determined. Eight extracts had IC50 values ranging from
ISSN:2314-6133
2314-6141
DOI:10.1155/2015/938747