Determining factors of diuresis in chronic kidney disease patients initiating hemodialysis

Patients with stage 5 chronic kidney disease (CKD) begin chronic hemodialysis with variable diuresis levels correlated to a comparable low glomerular filtration rate. Residual diuresis influences long-term evolution of the hemodialyzed patient, modifying the prognosis even if optimal Kt/ V is achiev...

Full description

Saved in:
Bibliographic Details
Published in:Journal of medicine and life 2015-07, Vol.8 (3), p.371-377
Main Authors: Nechita, A-M, Rădulescu, D, Peride, I, Niculae, A, Bratu, O, Ferechide, D, Ciocâlteu, A, Checheriță, I A, Mischianu, D
Format: Article
Language:English
Subjects:
Adult
Age Distribution
Aged
Albumins - metabolism
Case Presentations
Diuresis
Female
Glomerular Filtration Rate
Humans
Hypertension - complications
Hypertension - physiopathology
Male
Malnutrition - complications
Malnutrition - physiopathology
Middle Aged
Renal Dialysis
Renal Insufficiency, Chronic - complications
Renal Insufficiency, Chronic - physiopathology
Renal Insufficiency, Chronic - therapy
Systole
Young Adult
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Patients with stage 5 chronic kidney disease (CKD) begin chronic hemodialysis with variable diuresis levels correlated to a comparable low glomerular filtration rate. Residual diuresis influences long-term evolution of the hemodialyzed patient, modifying the prognosis even if optimal Kt/ V is achieved. The present study emphasizes the main determining factors of diuresis in a cohort of stage 5 CKD subjects at the beginning of hemodialysis. 216 patients with stage 5 CKD starting chronic hemodialysis were included in the study, and were grouped according to their residual diuresis: group A (urine output ≤ 500 mL/ day); group B (urine output between 500-1200 mL/ day); group C (urine output ≥ 1200 mL/ day). Glomerular etiology, cardiac systolic dysfunction, severe malnutrition, emergency dialysis initiation and lack of permanent vascular access were proved to be associated with significant low diuresis. Age, gender, estimated glomerular filtration rate (GFR) and the presence of systemic hypertension did not influence the amount of daily diuresis. In CKD stage 5 patients, residual diuresis presents large variations in conditions of comparable low GFR. Factors influencing residual diuresis may be distinct from those that influence residual GFR.
ISSN:1844-122X
1844-3117