Novel biomarkers of periodontitis and/or obesity in saliva—An exploratory analysis

Highlights • Levels of novel biomarkers were detectable in saliva periodontal recall patients. • Select biomarker levels correlate with periodontal and select obesity measures. • Correlations did not remain significant after adjusting for multiple comparisons. • Prospective studies with larger sampl...

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Bibliographic Details
Published in:Archives of oral biology 2015-10, Vol.60 (10), p.1503-1509
Main Authors: Recker, Erica N, Brogden, Kim A, Avila-Ortiz, Gustavo, Fischer, Carol L, Pagan-Rivera, Keyla, Dawson, Deborah V, Smith, Katherine M, Elangovan, Satheesh
Format: Article
Language:English
Subjects:
Advanced Basic Science
Aged
alpha-Fetoproteins - analysis
alpha-Fetoproteins - metabolism
Bbesity
Biomarkers - analysis
Biomarkers - metabolism
CD40 Ligand - analysis
CD40 Ligand - metabolism
Cross-Sectional Studies
Dentistry
Diagnostics
Female
Granzymes - analysis
Granzymes - metabolism
Humans
Interleukin 1 Receptor Antagonist Protein - analysis
Interleukin 1 Receptor Antagonist Protein - metabolism
Male
Middle Aged
Obesity - diagnosis
Obesity - metabolism
Periodontal disease
Periodontitis - diagnosis
Periodontitis - metabolism
Prospective Studies
Proteomics
Saliva
Saliva - chemistry
Saliva - metabolism
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Description
Summary:Highlights • Levels of novel biomarkers were detectable in saliva periodontal recall patients. • Select biomarker levels correlate with periodontal and select obesity measures. • Correlations did not remain significant after adjusting for multiple comparisons. • Prospective studies with larger sample sizes are warranted.
ISSN:0003-9969
1879-1506
DOI:10.1016/j.archoralbio.2015.07.006