Loading…

A novel actor in antitumoral immunity: The thymus-specific serine protease TSSP/PRSS16 involved in CD4+ T-cell maturation

The maturation of a specific subset of CD4 + T lymphocytes in the thymus is dependent on cortical thymic epithelial cells expressing the protease thymus-specific serine protease (TSSP, also known as PRSS16). Recently, we unveiled the involvement of TSSP in tumor suppression through its effect on the...

Full description

Saved in:
Bibliographic Details
Published in:Oncoimmunology 2015-09, Vol.4 (9), p.e1026536-e1026536
Main Authors: Brisson, Lydie, Carrier, Alice
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The maturation of a specific subset of CD4 + T lymphocytes in the thymus is dependent on cortical thymic epithelial cells expressing the protease thymus-specific serine protease (TSSP, also known as PRSS16). Recently, we unveiled the involvement of TSSP in tumor suppression through its effect on the CD4 + T compartment.
ISSN:2162-4011
2162-402X
2162-402X
DOI:10.1080/2162402X.2015.1026536