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A novel actor in antitumoral immunity: The thymus-specific serine protease TSSP/PRSS16 involved in CD4+ T-cell maturation
The maturation of a specific subset of CD4 + T lymphocytes in the thymus is dependent on cortical thymic epithelial cells expressing the protease thymus-specific serine protease (TSSP, also known as PRSS16). Recently, we unveiled the involvement of TSSP in tumor suppression through its effect on the...
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Published in: | Oncoimmunology 2015-09, Vol.4 (9), p.e1026536-e1026536 |
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Main Authors: | , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | The maturation of a specific subset of CD4
+
T lymphocytes in the thymus is dependent on cortical thymic epithelial cells expressing the protease thymus-specific serine protease (TSSP, also known as PRSS16). Recently, we unveiled the involvement of TSSP in tumor suppression through its effect on the CD4
+
T compartment. |
---|---|
ISSN: | 2162-4011 2162-402X 2162-402X |
DOI: | 10.1080/2162402X.2015.1026536 |