A Novel Methodology for the Simulation of Athletic Tasks on Cadaveric Knee Joints with Respect to In Vivo Kinematics

Six degree of freedom (6-DOF) robotic manipulators have simulated clinical tests and gait on cadaveric knees to examine knee biomechanics. However, these activities do not necessarily emulate the kinematics and kinetics that lead to anterior cruciate ligament (ACL) rupture. The purpose of this study...

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Bibliographic Details
Published in:Annals of biomedical engineering 2015-10, Vol.43 (10), p.2456-2466
Main Authors: Bates, Nathaniel A., Nesbitt, Rebecca J., Shearn, Jason T., Myer, Gregory D., Hewett, Timothy E.
Format: Article
Language:English
Subjects:
Athletics
Biochemistry
Biocompatibility
Biological and Medical Physics
Biomechanical Phenomena
Biomechanics
Biomedical and Life Sciences
Biomedical Engineering and Bioengineering
Biomedicine
Biophysics
Cadaver
Classical Mechanics
Computer Simulation
Humans
In vivo testing
Kinematics
Kinetics
Knee Joint - anatomy & histology
Knee Joint - physiology
Knees
Male
Models, Biological
Range of Motion, Articular - physiology
Simulation
Surgical implants
Tasks
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Summary:Six degree of freedom (6-DOF) robotic manipulators have simulated clinical tests and gait on cadaveric knees to examine knee biomechanics. However, these activities do not necessarily emulate the kinematics and kinetics that lead to anterior cruciate ligament (ACL) rupture. The purpose of this study was to determine the techniques needed to derive reproducible, in vitro simulations from in vivo skin-marker kinematics recorded during simulated athletic tasks. Input of raw, in vivo , skin-marker-derived motion capture kinematics consistently resulted in specimen failure. The protocol described in this study developed an in-depth methodology to adapt in vivo kinematic recordings into 6-DOF knee motion simulations for drop vertical jumps and sidestep cutting. Our simulation method repeatably produced kinetics consistent with vertical ground reaction patterns while preserving specimen integrity. Athletic task simulation represents an advancement that allows investigators to examine ACL-intact and graft biomechanics during motions that generate greater kinetics, and the athletic tasks are more representative of documented cases of ligament rupture. Establishment of baseline functional mechanics within the knee joint during athletic tasks will serve to advance the prevention, repair and rehabilitation of ACL injuries.
ISSN:0090-6964
1573-9686
DOI:10.1007/s10439-015-1285-8