Prediction of HIV Virologic Failure Among Adolescents Using the Pediatric Symptom Checklist

Psychosocial dysfunction is a risk factor for treatment non-adherence among children and adolescents. A previous study showed that high scores on the Pediatric Symptom Checklist (PSC) were associated with a history of HIV virologic failure. We assessed whether high scores on the PSC could predict vi...

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Bibliographic Details
Published in:AIDS and behavior 2015-11, Vol.19 (11), p.2044-2048
Main Authors: Lowenthal, Elizabeth D., Marukutira, Tafireyi, Tshume, Ontibile, Chapman, Jennifer, Anabwani, Gabriel M., Gross, Robert
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
Adolescent
Adolescents
AIDS
Anti-HIV Agents - therapeutic use
Botswana - epidemiology
Brief Report
Caregivers
Checklist
Child
Children
Children & youth
Failure
Female
Health Psychology
HIV
HIV Infections - drug therapy
HIV Infections - virology
Human immunodeficiency virus
Humans
Infectious Diseases
Male
Mass Screening
Medicine
Medicine & Public Health
Pediatrics
Predictive Value of Tests
Prospective Studies
Psychological aspects
Psychosocial factors
Public Health
Resource utilization
Risk
Risk analysis
Risk Factors
Social psychology
Surveys and Questionnaires
Treatment compliance
Treatment Failure
Viral Load - drug effects
Virology
Youth
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Summary:Psychosocial dysfunction is a risk factor for treatment non-adherence among children and adolescents. A previous study showed that high scores on the Pediatric Symptom Checklist (PSC) were associated with a history of HIV virologic failure. We assessed whether high scores on the PSC could predict virologic failure in HIV-infected youth. Caregivers of 234 adolescents between the ages of 10 and 16 years were asked to complete a PSC at baseline. Elevated PSC scores were associated with virologic failure in the subsequent 6 months. PSC scores may help guide resource utilization when viral load monitoring is limited.
ISSN:1090-7165
1573-3254
DOI:10.1007/s10461-015-1061-7