HAART, DOTS and renal disease of patients co-infected with HIV/AIDS and TB in the South West Region of Cameroon

Tuberculosis is the commonest infection among HIV/AIDS patients. This co-infection constitutes a major death threat in the world. There is paucity of data about renal disease amongst patients on HAART and DOTS therapy in Cameroon. This was a hospital-based cross-sectional study in the Buea, Limbe an...

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Bibliographic Details
Published in:BMC public health 2015-10, Vol.15 (1), p.1040, Article 1040
Main Authors: Nsagha, Dickson Shey, Pokam, Benjamin Thumamo, Assob, Jules Clement Nguedia, Njunda, Anna Longdoh, Kibu, Odette Dzemo, Tanue, Elvis Asangbeng, Ayima, Charlotte Wenze, Weledji, Patrick Elroy
Format: Article
Language:English
Subjects:
Acquired Immunodeficiency Syndrome - drug therapy
Acquired Immunodeficiency Syndrome - epidemiology
Adult
Aged
Albumin
Antiretroviral Therapy, Highly Active - statistics & numerical data
Cameroon - epidemiology
Coinfection - embryology
Coinfection - epidemiology
Communicable Diseases - epidemiology
Cross-Sectional Studies
Female
Health aspects
HIV Infections - epidemiology
Humans
Kidney Diseases - drug therapy
Kidney Diseases - epidemiology
Kidney Function Tests
Lamivudine
Logistic Models
Male
Middle Aged
Nevirapine - therapeutic use
Physiological aspects
Prevalence
Public health
Tuberculosis, Pulmonary - drug therapy
Tuberculosis, Pulmonary - epidemiology
Young Adult
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Summary:Tuberculosis is the commonest infection among HIV/AIDS patients. This co-infection constitutes a major death threat in the world. There is paucity of data about renal disease amongst patients on HAART and DOTS therapy in Cameroon. This was a hospital-based cross-sectional study in the Buea, Limbe and Kumba government Hospitals. Spectrophotometric method was used for the quantitative determination of serum creatinine, urea, albumin and total protein levels. Glomerular filtration rate was estimated using the MDRD method. The student's t test, ANOVA and logistic regression were used to analyse the data. Out of 200 participants, 101 (50.5 %) were males. The ages ranged from 21 to 65 years with a mean age of 38.04 ± 10.52 years. Compared to adults on DOTS alone, adults on HAART alone had a significantly higher prevalence of eGFR
ISSN:1471-2458
1471-2458
DOI:10.1186/s12889-015-2331-z